Batejat DM, Lagarde DP
Institut De Medecine Aerospatiale du Service De Sante Des Armees, Bretigny sur
Orge, France.
Aviat Space Environ Med 1999 May;70(5):493-8
ABSTRACT
Disruptions in wake-sleep rhythms,
particularly induced by sleep deprivation are limiting factors for military
personnel in operations. The role of sleep and naps in the recovery of
performance is generally accepted. Pharmacological aids, for example hypnotic
or stimulant substances can also be effective countermeasures. Recently, a new
stimulant compound, modafinil (MODIODAL) has also proven effective.
Considering the excellent results obtained with napping and modafinil, we have
studied the combined effect of these two countermeasures on psychomotor
performance under conditions simulating an operational situation. Beneficial
effects of a few hours' nap on performance were confirmed. Consequently naps
should be encouraged, even if limited and diurnal. Modafinil, which combines
wakening and stimulating properties without any known side effects, was useful
for longer periods of sleep deprivation and when there was no real possibility
of sleep recovery. Modafinil did not prevent sleep if sleep opportunities were
available. The combination of naps and modafinil demonstrated the best
cognitive performance during sleep deprivation.
1. modafinil is
a potential treatment for
fibromyalgia
2. modafinil improves
fatigue in patients with multiple sclerosis
3. modafinil offers
promise as an augmentation to antidepressants
4. modafinil excessive sleepiness in
Parkinson's disease
5. modafinil excessive
daytime sleepiness in Parkinson's disease
6. modafinil may
be useful for attention-deficit/hyperactivity disorder
7. modafinil benefits
cerebral palsy in an unknown way
8. modafinil
article
9. modafinil
amplification of cortical serotonin release
10. modafinil
treatment of alcoholic organic brain syndrome
11. modafinil
effect on melatonin, cortisol, and growth hormone
12. modafinil
in obstructive sleep apnea-hypopnea syndrome
13. modafinil
vs dextroamphetamine in treatment of adult ADHD
14. modafinil
efficacy in narcolepsy
15. modafinil
switching from narcolepsy drugs to modafinil
16. modafinil
drug of choice for narcolepsy
17. modafinil
dopaminergic transmission mediates CNS stimulants
18. modafinil
for daytime sleepiness in sleep apnea
19. modafinil
treatment of residual excessive daytime sleepiness
20. modafinil
in the treatment of
narcolepsy
21. modafinil
and naps as counter measures in sleep deprivation
22. modafinil
effect on narcolepsy
23. modafinil
as a treatment for excessive daytime sleepiness
24. modafinil
a narcolepsy study
25. modafinil
use in a sleep deprivation experiment
26. modafinil for
sustaining the alertness of helicopter pilots
27. modafinil the
unique properties of a new stimulant
28. modafinil dosage
and safety
29. modafinil in treatment of fatigue in
multiple sclerosis
30. modafinil non-addictive potential of modafinil
31. modafinil successful
treatment of hypersomnia & narcolepsy
32. modafinil physiological effects of modafinil in drug abusers
33. modafinil narcolepsy:
symptoms and management
34. modafinil cognitive enhancing effects of modafinil
