Lyons TJ, French J
Headquarters USAF Human Systems Division,
Brooks Air Force Base, TX 78235.
Aviat Space Environ Med 1991
May;62(5):432-5
ABSTRACT
Modafinil, a novel stimulant which has several remarkable features that
distinguish it from other stimulants, has been developed by Lafon, a French
pharmaceutical company. Unlike the amphetamines, for example, modafinil
is
reported to have minimal peripheral side effects at therapeutic doses. It also
appears to have a low abuse potential, does not interfere with normal sleep,
and does not seem to produce tolerance. Modafinil
improves vigilance especially in
sleep-deprived subjects. It has been used clinically for up to 3 years in the
treatment of narcolepsy and idiopathic hypersomnia. It could be an ideal
replacement for amphetamine in short-term operations in which fatigue might
threaten the successful completion of a mission. We recommend that military
laboratories experienced in studying sustained performance include modafinil
or perhaps a more selective alpha 1 receptor agonist in their investigations.
1. modafinil is
a potential treatment for
fibromyalgia
2. modafinil improves
fatigue in patients with multiple sclerosis
3. modafinil offers
promise as an augmentation to antidepressants
4. modafinil excessive sleepiness in
Parkinson's disease
5. modafinil excessive
daytime sleepiness in Parkinson's disease
6. modafinil may
be useful for attention-deficit/hyperactivity disorder
7. modafinil benefits
cerebral palsy in an unknown way
8. modafinil
article
9. modafinil
amplification of cortical serotonin release
10. modafinil
treatment of alcoholic organic brain syndrome
11. modafinil
effect on melatonin, cortisol, and growth hormone
12. modafinil
in obstructive sleep apnea-hypopnea syndrome
13. modafinil
vs dextroamphetamine in treatment of adult ADHD
14. modafinil
efficacy in narcolepsy
15. modafinil
switching from narcolepsy drugs to modafinil
16. modafinil
drug of choice for narcolepsy
17. modafinil
dopaminergic transmission mediates CNS stimulants
18. modafinil
for daytime sleepiness in sleep apnea
19. modafinil
treatment of residual excessive daytime sleepiness
20. modafinil
in the treatment of
narcolepsy
21. modafinil
and naps as counter measures in sleep deprivation
22. modafinil
effect on narcolepsy
23. modafinil
as a treatment for excessive daytime sleepiness
24. modafinil
a narcolepsy study
25. modafinil
use in a sleep deprivation experiment
26. modafinil for
sustaining the alertness of helicopter pilots
27. modafinil the
unique properties of a new stimulant
28. modafinil dosage
and safety
29. modafinil in treatment of fatigue in
multiple sclerosis
30. modafinil non-addictive potential of modafinil
31. modafinil successful
treatment of hypersomnia & narcolepsy
32. modafinil physiological effects of modafinil in drug abusers
33. modafinil narcolepsy:
symptoms and management
34. modafinil cognitive enhancing effects of modafinil
