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Beginners Guide to Mixing L-theanine & Adderall

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Adderall helps manage ADHD and narcolepsy, but some people often experience unwanted side effects such as anxiety, jitters, and insomnia after taking it. To mitigate these adverse reactions, as well as to enhance cognitive function, some individuals mix it with L-theanine, a natural amino acid commonly found in green tea.

Guide to Mixing L-theanine & Adderall

If you’re considering mixing both substances, it is essential to first learn about the potential benefits, possible interactions, and whether it is even safe to take them together.

Adderall Features

Adderall is a prescription medication that contains two central nervous system (CNS) stimulants: amphetamine and dextroamphetamine. It was accidentally discovered in the 1920s; a new and improved version was approved by the Food and Drug Administration (FDA) in 1996 to manage symptoms of narcolepsy and attention deficit hyperactivity disorder (ADHD), as it can improve alertness, attention, and wakefulness [1][2].

The drug is available in two formulations: immediate-release (Adderall IR) tablet and extended-release (Adderall XR) capsule. The immediate-release version of the drug is available in 7 dose strengths, including 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg, 20 mg, and 30 mg. On the other hand, Adderall XR comes in 6 dose strengths: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg [3].

Adderall’s mechanism of action is based on its ability to increase the levels of dopamine and certain other neurotransmitters in the brain. While it is safe and effective when used correctly, it remains important to use it with caution to avoid unwanted side effects. The drug is approved for use in both children and adults alike; however, it is not safe for individuals with certain underlying medical conditions. Consult your doctor before starting treatment with the med.

What Is L-Theanine?

L-theanine is an amino acid that is popularly known for its calming and relaxing effects. It is naturally found in black tea, green tea leaves, and some mushrooms, and extracted for use in anxiety and stress reduction. It is known to increase the levels of gamma-aminobutyric acid (GABA), dopamine, and serotonin, neurotransmitters that aid in regulating mood and anxiety. L-theanine is also thought to provide cognitive benefits such as increased alertness & focus, as well as an increased feeling of well-being [4][5].

L-Theanine Pills

It is worth noting that some of the effects of this substance are purely based on the accounts of users. There are only a handful of studies that support its safety and effectiveness. It is advisable to consult a doctor before starting treatment with it.

Using Adderall and L-Theanine Together

Adderall and L-theanine can have complementary effects when used together. The amino acid may help reduce some of the negative after-effects of Adderall, such as restlessness, tremor, anxiety, etc. Also, there is the possibility of it enhancing concentration and boosting focus. Many people have reported feeling more focused and alert after combining both substances [6].

However, before jumping into trying out the combination, it is worth noting that the resultant effects can vary from individual to individual based on different factors. Age, sex, weight, genetic makeup, and underlying medical conditions are a few factors that may determine the effects. It is also important to consider the safety and possible adverse effects & interactions that can result from the combination. Let’s explore these areas.

Is This Combo Safe?

It is hard to say whether the mix is safe, as there is limited research on the safety of combining both substances. However, both of them are generally considered safe when used exactly as directed. Many people who have tried the combo reported experiencing no serious adverse effects. Regardless, it is important to talk to a doctor before combining them or any medications or supplements.

If Adderall is causing you too many adverse reactions, your doctor may recommend alternatives such as modafinil and armodafinil, especially if you’re taking it to treat narcolepsy. To improve alertness and promote wakefulness, these drugs block the reuptake of dopamine, ultimately increasing its concentration in the brain to desirable levels. They are generally safer and have fewer adverse effects than Adderall.

Positive Effects of Drug Mixing

Some people have reported experiencing a range of positive effects after mixing L-theanine and Adderall. The most talked about effects include improved focus & attention, reduced restlessness & anxiety, and an increased sense of calm and alertness.


However, it is worth noting that the effects can vary depending on the individual mixing them and the dosage of the individual substances administered.

Possible Side Effects

Adderall and L-theanine have their individual side effects, so when combined, there is an increased potential for negative consequences. Some users may experience mild symptoms such as dizziness, headaches, and nausea. In some cases, although rare, more serious adverse effects such as heart problems and seizures may occur. It is important to seek urgent medical attention if you experience any of these negative reactions.

Interactions with Food, Alcohol, and Other Drugs

Both L-theanine and Adderall interact with alcohol, certain foods, and some drugs individually. It is important to be aware of all the substances they interact with and avoid them. For example, Adderall is known to interact with caffeine and other stimulants or stimulant-like meds, such as modafinil & armodafinil, while L-theanine interacts with antidepressants & blood pressure meds. It is important to avoid all of these things when mixing both substances.

So, Can You Take L-theanine with Adderall?

One of the questions many Adderall users ask is, Can you take it with L-theanine? The answer is yes. L-theanine is thought to have a calming effect due to its ability to increase alpha waves in the brain. This is not to mention the corrective role it can play against the adverse effects of Adderall. You are likely to find the combination helpful if Adderall is causing you side effects such as sleep disturbances and anxiety. Some individuals who take both substances together have reported experiencing numerous benefits like improved focus and increased alertness.

However, it is important to note that there is limited research on benefits, possible adverse effects, risk of withdrawal, and interactions between L-theanine and Adderall. More studies need to be carried out to establish the optimal dosage and timing for combining them. At this point, it is worth noting that the effects of the combo can be influenced by how much of each substance you take in the stack and your tolerance.

As a rule of thumb, it is a good idea to start with low doses and monitor your symptoms as you go. As with starting treatment with any new supplement or stacking medications, it is always advisable to consult a doctor before combining these substances.


  1. Adderall. Retrieved: March 10, 2023.
  2. Generation Adderall. By Casey Schwartz. Retrieved: March 10, 2023.
  3. Adderall Dosage, Costs, Side Effects, and More. Retrieved: March 10, 2023.
  4. One Supplement You Should Start Taking Now. By Kristin Bundy. Retrieved: March 10, 2023.
  5. Caffeine and L-Theanine: Nootropics You Didn’t Know You Were Using. Retrieved: March 10, 2023.
  6. Theanine and Adderall. By P. Tardner. Retrieved: March 10, 2023.