Modafinil is a versatile medication.
It’s a prescription medication used for treating narcolepsy and obstructive sleep apnoea, but has a wide range of “off-label” uses.
Over the past decade, there’s been an increased interest in modafinil as a treatment for ADHD. It’s often preferred over alternatives because it’s less likely to result in tolerance and addiction.
Is modafinil effective for treating ADHD? How do I get started?
What is ADHD?
ADHD is characterized by symptoms involving an inability to pay attention, impulsive behavior, and hyperactivity. It’s a common condition in children and can sometimes extend into adulthood.
According to one study, roughly 6% of children suffer from ADHD .
This disorder is complicated and there are many factors that might cause the condition.
There is a major genetic component to ADHD. In 75-91% of cases of ADHD, a familial or genetic connection can be easily identified. .
A recent study compared the genes of ADHD sufferers to look at dopamine function .
The study looked at 3 specific genes:
- DAT1 (Dopamine transporter gene)
- DRD4 (Dopamine receptor 4)
- DRD5 (Dopamine receptor 5)
Researchers in this study found common genetic variations of ADHD sufferers on all 3 of these genes.
Why This is an Important Finding
What we can take away from research like this is that ADHD has a significant relationship to dopamine. This means that when it comes to treating the condition we can try to address the issues caused by the gene variations.
This research offers a good explanation for why drugs that tend to benefit ADHD the most also tend to boost dopamine levels.
This includes Adderall, Ritalin, Concerta, AND modafinil.
Modafinil for ADHD
Although modafinil is sometimes used by doctors to treat ADHD, it’s considered “off-label use” in the United States. It hasn’t yet been approved by the FDA for this use.
Modafinil and Dopamine
Modafinil has been shown to increase dopamine concentrations in the brain . It does this in a similar way to other common ADHD medications like Ritalin and Adderall, both of which have a long history of use for treating ADHD in conventional medicine.
Modafinil increases dopamine concentrations in the synapses by preventing the neurons from reabsorbing and breaking it down.
Normally, dopamine is released to exert its effect, then promptly reabsorbed and broken down. modafinil prevents the reabsorption and breakdown stages, allowing it to exert its effects for LONGER.
Dopamine is extremely important for the mind to be able to focus on one thing at a time.
This is because dopamine is involved in the reward center of the brain. This is a special region within the brain that causes a release of “feel good” molecules like oxytocin as a way to reward useful behaviors. This is how habits are formed.
Our brain LOVES getting rewarded and will seek behaviors that trigger this response.
Dopamine & Addiction
Unfortunately, the dopamine-regulated reward center is also responsible for addiction.
Many illicit compounds trigger the reward system due to their relaxing or pain-relieving benefits. This causes a release of oxytocin in the brain as part of the reward. After a while, the brain starts to crave the things that cause this oxytocin release and we become addicted to the drug.
We can also become addicted to exercise, sex, or eating through these same effects.
ADHD & The Reward Center
Most people have sufficient dopamine levels and are able to trigger the reward center effectively. This makes it easy to build habits and remain focused on the same thing for longer periods of time.
People with ADHD have issues with this system and need to work extra hard to get positive feedback in the reward center of the brain.
Concentrating on one task for more than a few minutes can be difficult as the brain seeks out more stimulating activities.
If dopamine levels increase, we may be able to lower the threshold for activation of the reward center.
This would help prevent the fidgeting and jitteriness associated with ADHD sufferers.
Treating Overstimulation With Stimulants?
It may seem strange that you can treat overstimulation with a stimulant, however, there is a perfectly reasonable explanation for this.
As people suffering from ADHD have a hard time stimulating the reward response in the brain, it causes them to self-stimulate by fidgeting or moving around.
Where to Buy Modafinil
There are many online modafinil suppliers.
Few of them, however, are of any real quality. Many are fake copycat websites hoping to steal your credit card or Bitcoin payments.
We recommend going directly to Afinil.com for your modafinil.
We have a lot of experience with them and have always found them to be a reliable and affordable source of modafinil and armodafinil.
They offer free shipping and guaranteed delivery to most countries. If your order is confiscated at the border, or lost in the mail, Afinil.com will either reship the package or refund your order.
In most cases, your package will be delivered on time. On some occasions, border security will screen and withould the shipments from their final destination until a prescription is shown.
If the prescription isn’t produced, the package will eventually be destroyed.
If this happens to you, simply reach out to customer service at Afinil.com and they will sort out a solution for you. In most cases, they will either offer a full refund on the order or they will re-ship an identical order.
It’s very rare that a package is confiscated twice in a row.
ADD vs ADHD
ADD and ADHD are very similar and are often used synonymously with each other.
The difference that sets the two apart is the presence of hyperactivity.
Some people with attention deficit disorder (ADD) have hyperactivity (fidgeting, frequent movements, inability to sit still), while others remain calm.
Depending on whether hyperactivity is present or not will determine whether the diagnosis is ADD or ADHD.
Although the treatment for both is roughly the same, ADHD often involves specific treatments aimed at the hyperactivity side of the condition.
How to Use Modafinil for ADHD
Using Modafinil for ADHD is simple. Doses of either 100 mg or 200 mg are taken by adults to offset the symptoms of ADD or ADHD.
There are 2 ways Modafinil can be used for this condition:
1. Daily Use
This is the most common dosing regimen for ADHD sufferers. A daily dose of 100 – 400 mg of modafinil can be used to reduce symptoms and increase concentration.
The problem with this is the development of tolerance.
If a drug is used frequently over long periods of time, the body often starts to resist its effects. This means that more modafinil will need to be taken than usual to produce the same effects.
If you plan on using modafinil daily, it’s recommended that you first discuss your condition and the options available with your doctor.
After consulting with your doctor, we recommend buying your modafinil online from a generic medication supplier like Afinil.com. This is going to be the most cost effective and simple method available both WITH or WITHOUT a prescription.
2. Periodic Use
Some ADHD sufferers choose to use their modafinil periodically as they need it.
They would keep some on hand for days that they know they need to be productive, such as during school, at work, or while at home studying for an exam.
The benefits of taking modafinil periodically (1-4 times per week) is that it can significantly reduce the chances of developing tolerance to the medication.
We recommend buying your modafinil from Afinil.com.
What Does Modafinil Feel Like?
Modafinil feels like a strong cup of coffee.
It’s not as stimulating on the body as older ADHD medications like Adderall or Ritalin, but it does produce profound feelings of stimulation on the brain.
When studying or working, it becomes much easier to remain intently focused on the work at hand. You no longer feel as strong an urge to get up and go somewhere else or flip open your Facebook and become entrenched in memes and pictures of your friend’s recent vacation to Bali.
How Long Does Modafinil Last?
Modafinil’s effects can vary a lot from one person to the next depending on their size, whether they ate a meal or not, and how big the dose was.
Most users will begin to feel the effects of modafinil about an hour after ingestion.
For the next 3 hours, the effects begin to gradually increase and reach a peak. The next 7-14 hours the drug slowly starts to wear off.
A 200 mg modafinil tablet will produce effects lasting about 12-15 hours. In some cases, it can last as long as 20 hours.
What are the Downsides to Using Modafinil for ADHD?
In some people, modafinil can cause anxiety or insomnia.
Although this is a common problem and can usually be avoided by simply taking the modafinil earlier in the day, some people can’t seem to avoid it.
If you experience frequent anxiety or insomnia while taking modafinil, try taking some time off the drug every week (such as a day or two) or lower your dose.
Most people find improvement when they take their tablet sooner in the day.
If you continue to have problems with anxiety or insomnia, it may be best to look for another treatment option.
Other Areas to Consider When Treating ADHD
ADHD is strongly connected to problems with dopamine, but also has other factors that need to be considered.
Diet has also been shown to play a major role in the development of ADHD .
Nutritional research has found that people with ADHD should avoid foods containing high-refined carbohydrates and sugars, as well as salt, added food dyes and coloring agents.
Potential allergies should also be investigated and avoided.
- Li, D., Sham, P. C., Owen, M. J., & He, L. (2006). Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human molecular genetics, 15(14), 2276-2284.
- Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., & Sklar, P. (2005). Molecular genetics of attention-deficit/hyperactivity disorder. Biological psychiatry, 57(11), 1313-1323.
- Shastry, B. S. (2004). Molecular genetics of attention-deficit hyperactivity disorder (ADHD): an update. Neurochemistry international, 44(7), 469-474.
- Ferraro, L. N., Antonelli, T., O’Connor, W., Tanganelli, S., Rambert, F. A., & Fuxe, K. (1997). Modafinil: an anti narcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers. Biological psychiatry, 42, 1181-1187.
- Jacobson, M. F., & Schardt, D. (1999). Diet, ADHD & Behavior: A Quarter-Century Review [and] A Parent’s Guide to Diet, ADHD & Behavior.