Modafinil Dosage Guide: 50-400+ mg Doses

Modafinil is a cognitive performance-enhancing medication. It’s popular among students and corporate employees for boosting their efficiency and helps them power through tough projects.

When a doctor prescribes Modafinil, they provide detailed instructions on dosages for their specific use. People ordering their Modafinil online, however, are often left guessing about what the best dose might be for their medication. 

Today we’re going to have a look at the common dosages among the most popular Modafinil products available from vendors like afinil.com.

We go through how much you should take depending on what your motivation for taking it is and highlight a basic dosage schedule to get the best results possible from your medications.

The 2 Types of Modafinil

In order to talk about doses, we need to differentiate the 2 different types of Modafinil available; Modafinil and Armodafinil.

Both contain the Modafinil compound as the active ingredient but have some subtle differences.

Modafinil is considered a “racemic” compound by chemists. This basically means that it contains 2 isomers of the same compound. Isomers are different variations of the same chemical. Just like your right and left hand are different variations of the same thing (a hand), the two are virtually identical in every way except that they are mirror images of each other.

Armodafinil, however, is considered to be “enantiopure”, which means that it only contains one type of isomer— the R- isomer. This isomer is considered to be slightly stronger than the S- isomer, making the overall effects of Armodafinil slightly stronger than Modafinil.

Differences In Dosages Between Armodafinil and Modafinil

The first differentiation to discuss is the difference in dose between the 2 types of Modafinil. The standard dose for Modafinil is 200 mg, while the equivalent dose of Armodafinil is slightly lower at 150mg.

Even at this dose, Armodafinil is considered to be slightly more intense than Modafinil.

Dosage Range Comparison of Modafinil & Armodafinil

Lowest Effective Dosage

Most Common Dosage

Highest Dosage Limit

Modafinil

50mg 200mg 400mg

Armodafinil

50mg 150mg 250mg

Where To Buy Modafinil Online

There are many online sources for Modafinil, however, due to the poor regulations in this industry, the market is saturated with low-quality vendors.

There are some exceptions that are offering high-quality Modafinil and Armodafinil at competitive rates.

Our favorite vendor is afinil.com, for 3 main reasons:

1. They Offer Free Shipping

One of the best parts about Afinil.com is that they offer free shipping on all of their orders. This goes a long way when you consider the fact that they’re shipping all the way from India. We believe this is a great representation of how Afinil.com values their customers.

2. They Have Excellent Customer Service

We’ve reviewed numerous other online vendors and a common theme with many of the poor quality ones was poor customer service. Orders would be paid for, but no confirmation would be sent. Customers report reaching out to customer service to confirm their order had been placed with zero response from the company. Sometimes, the package would show up 3-8 weeks later, other times it wouldn’t, and there was nothing anybody could do about it.

This is completely unacceptable.

Afinil.com makes an effort to contact customers of any delays and remains well reachable should there be any concerns of questions. Every time we made an order, we received clear confirmation that the payment went through, and they even provided updates on the order.

3. They Sell High-Quality Modafinil

Another problem many people have been experiencing lately is low-quality Modafinil. If you have to ask what Modafinil feels like after a 200mg dose, you’ve likely received low-quality Modafinil. There’s nothing worse than spending $200 on an order, waiting 2 weeks to get it, and then have it not work the way it’s supposed to.

Afinil.com offers excellent quality Modafinil. They batch test their products and ensure that only the best quality products leave their warehouse. They understand that it only takes a few low-quality reviews to ruin their reputation and take extreme measures to prevent this from happening.

Visit Afinil.com now

Doses For Modafinil

Dose For ADHD & Narcolepsy

The average prescribed dose for Modafinil for both narcolepsy and ADHD is 200mg Modafinil or 150 mg Armodafinil. In some cases, this can be as high as 500 mg for Modafinil and 250 mg Armodafinil. [1, 2].

Dosage Range For Cognitive Enhancement

The dosage range for Modafinil cognitive enhancement benefits can range from 50mg to 400 mg depending on what the user’s motivations for taking it are. Other factors that come in include patient size, how reactive they are to the drug, and how often they’re taking it.

Using Smaller Doses For Cognitive Enhancement (50mg)

Some people prefer to take their Modafinil in smaller doses. This will produce the weakest effects initially, but it’s the safest option for long-term use.

Any dose that is 50 mg or less is considered a microdose. These doses offer much fewer effects than the normal 100, 200, or 400 mg doses but can provide benefits over longer periods of time.

Many people use this dose for long periods of time as a caffeine replacement to help them wake up in the morning. It promotes a gentle, low-grade feeling of wakefulness about 30-45 minutes after consumption.

Modafinil doesn’t usually come in 50 mg tablets. In order to get this dose, 100mg tablets will need to be broken in half, or 200 mg doses will need to be broken in quarters. It’s much easier to break a 100mg tablet in half than it is to break a 200 mg in fourths. The manufacturer usually makes a crease down the middle to help users split the tablets in half evenly.

Some users mash their capsules up into a powder and split this into 4 equal portions. The powder can then be encapsulated or blended into a strong smoothie in the morning. This method will dramatically lower the time it takes for the Modafinil to enter the bloodstream, and allows effective control of smaller doses.

The equivalent Armodafinil dosage in this range is also 50 mg but can be slightly stronger in its effects.

50 mg Modafinil Dose Benefits:

  • Best for people who are more sensitive to Modafinil
  • Useful for people just starting out with Modafinil to test its effects
  • The best option for long-term consecutive use (years)
  • Has the lowest chances of developing side effects

Average Doses For Cognitive Enhancement (200mg)

This is the most popular dosage used for cognitive enhancement. It comes to no surprise that this is also the most common dosage form found online.

Afinil.com offers 200 mg versions of both Waklert and Modvigil.

This is also the dosage with the most research behind it.

The equivalent Armodafinil dose to this is 150 mg, which is the dosage supplied in the generic versions Artvigil and Modvigil, both found on afinil.com.

200mg Dose Benefits:

  • Provides well-known effects on cognition
  • Has a great deal of research behind this dosage
  • Easiest dosage to take (no splitting or powdering of pills needed)

Larger Doses For Cognitive Enhancement (400mg)

In some cases, larger doses of Modafinil are desired. 400mg, however, is considered the highest safe dose. Anything over 400mg dramatically increases the risk of side effects.

A 400mg dose of Modafinil is useful for larger individuals or people who have developed a tolerance to Modafinil with long-term use.

This dosage is NOT recommended for people just starting out. It can produce significant anxiety, insomnia, and other side effects. If you wish to try this dose, even if you have a larger than average build, you should always build the dose up slowly from either 50 mg or 100 mg. This is done to make sure you aren’t allergic or hypersensitive to the compound.

The equivalent Armodafinil dose to this is 250 mg. Most tablets are supplied in 150 mg doses, making it easier to double up and take a 300 mg dose. Users should be aware that this will be stronger in its effects compared to the equivalent 400 mg Modafinil.  

400 mg Dose Benefits:

  • The strongest effects within the safe dosage range
  • Best for people with large builds
  • Best for people with fast drug metabolism
  • Best for short term use of Modafinil

Side Effects Of Modafinil

There are a number of side effects associated with Modafinil. Most of them are only subtle, such as insomnia, mild gastrointestinal upset, headaches, low appetite, and dry mouth.

These side effects are more likely to occur with higher doses.

The 50 mg dose rarely produces any side effects, while the 400 mg dose often produces side effects of insomnia and headaches.

Side effects can be ameliorated by taking the medication earlier in the day and away from other stimulants like coffee or tea. Drinking plenty of water (2-3 L per day), as well as sufficient nutrition throughout the day, will go a long way in eliminating or preventing side effects.

When To Visit A Doctor

More severe side effects have been reported, but they are much rarer.

If you are experiencing any symptoms of hysteria, difficulty breathing, dizziness, hallucinations, or severe skin reactions, you should visit a doctor immediately.

Recommended Dosage Schedule For New Users

Whenever trying a supplement or medication out for the first time, it’s recommended that you start with a smaller dose and build up gradually to a higher dose. This is done to make sure that you’re not allergic to the drug and that you can metabolize and eliminate it from your body effectively.

Almost all drugs that enter the body are metabolized by the liver. The liver uses a set of enzymes to break down chemicals. Each one is coded by a specific gene, which we refer to as the CYP450 isoenzymes.

Everyone’s CYP450 genes are unique (polymorphisms) and some people have a stronger ability to break down certain chemicals than others.

This is why many people can drink coffee all day long, while others seem to remain wired for hours after just one cup. They’re essentially unable to break the caffeine down as efficiently due to the CYP450 polymorphisms they possess.

The same can happen with Modafinil, which is why it’s best to make sure there are no problems before jumping straight into a large 400 mg dosage right off the start.

If you have difficulty metabolizing Modafinil, its effects will last much longer. Additionally, if taking Modafinil every day, the concentrations in your bloodstream can begin to build up over time.

Recommended Dosage Schedule For New Modafinil Users

Week

Dose

Any Side Effects?

1 50 mg If yes, Modafinil may not be for you.
2 100 mg If yes, go back to 50mg per day.
3 200 mg If yes, try 150 mg per day.
4 300 mg If yes, try 250 mg per day.
5 350 mg If yes, go back to 300 mg per day.
6 400 mg If yes, go back to 350 mg per day.

 

Conclusion

Modafinil can be an extremely useful medication to boost your workflow and productivity. People often use it to get a step ahead of their colleagues or competition and to boost their overall performance at work or school.

Due to the potential for side effects, proper dosage is very important with this drug.

We recommend starting at a small 50mg or 100 mg dose the first few days before increasing this dose. The normal dosage range for Modafinil (Modalert & Modvigil) is 100-400mg per day). The equivalent doses of Armodafinil (Waklert & Artvigil) is 50-250mg per day.

It’s also recommended that you always ensure you’re consuming enough food and water throughout the day to avoid any potential side effects.

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References

  1. Bastoji, H., & Jouvet, M. (1988). Successful treatment of idiopathic hypersomnia and narcolepsy with modafinil. Progress in neuro-psychopharmacology and biological psychiatry, 12(5), 695-700.
  2. Harsh, J. R., Hayduk, R., Rosenberg, R., Wesnes, K. A., Walsh, J. K., Arora, S., … & Roth, T. (2006). The efficacy and safety of armodafinil as treatment for adults with excessive sleepiness associated with narcolepsy. Current medical research and opinion, 22(4), 761-774.
  3. Biederman, J., Swanson, J. M., Wigal, S. B., Kratochvil, C. J., Boellner, S. W., Earl, C. Q., … & Greenhill, L. (2005). Efficacy and safety of modafinil film–coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, flexible-dose study. Pediatrics, 116(6), e777-e784.

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