Modafinil & Viagra: What to Expect from Mixing Drugs?

Due to every individual’s distinctive body chemistry, modafinil might affect your sex life differently – either positively or negatively. There are no confirmed investigations regarding modafinil & sex currently or mixing modafinil and sexual dysfunction meds such as Viagra. However, some anecdotal evidence depicts that modafinil may be helpful during intercourse.

In this guide, we discuss the use of modafinil and Viagra together, their benefits, expected negative effects, & the verdict. But first pointers first.

What Is Modafinil?

It’s the king of nootropics, dubbed a “smart tab.” The FDA approves it for treating sleep disorders due to shift work sleep disorder, narcolepsy, & obstructive sleep apnea. Off-label, physicians can prescribe modafinil for conditions such as weight loss, depression, everyday cat-napping, chronic fatigue, ADHD, jet lag, age-related memory decline, Parkinson’s & Alzheimer’s disease, multiple sclerosis-induced fatigues, myotonic dystrophy, cognitive impairment in schizophrenia, idiopathic hypersomnia, post-anesthesia grogginess, etc. But nowadays, it’s popularly used by healthy enthusiasts such as students, CEOs, professionals, military personnel, factory workers, astronauts, etc., as a cognitive augmenter & productivity ameliorator to achieve an edge.

Impressively, modafinil offers a lot of advantages such as ameliorated focus, alertness, boosted memory, mental acuity, motivation, positive mood, swift planning skills, reasoning, decision-making, etc.

Its working aspect is that it inhibits dopamine reuptake (thus ameliorating concentration), ameliorates orexin concentrations (hence heightening wakefulness & vigilance), inhibits norepinephrine reuptake for benefits such as heightened mental energy, & also ameliorates histamine levels with rewards such as fostered wakefulness. There can be several other benefits of modafinil use, with a half-life of 12-15 hours [1].

Modafinil is available in doses of 200 & 100 mg. The former one is the typical starting dose, & it can be lessened to 100 mg if the 200 mg is robust.

Safe dosage means consulting with a physician to assess your health and determine if modafinil is fit for you, even if taking it off-label.

What Is Viagra?

Viagra® is a product of Pfizer pharmaceutical. It comprises sildenafil as its active component. Viagra was a rousing triumph from its rocking finding. The moment it came on the market as the first erectile dysfunction (ED) med, having been authorized by the U.S. Food and Drug Administration (FDA), it helped millions of men globally treat ED & lead a relished sex life.

Impotence transiently influences nearly all males at some point as they age. This situation transpires at any age.

It’s obtainable in doses of 25, 50, & 100 mg tabs. The suggested starting quantity is 50 mg or lower. Nonetheless, if the 50 mg tab is overly robust or is not well-tolerated, you can modify it to 25 mg. The 100 mg is the most suitable tab for men with chronic ED that don’t respond pleasingly to the 50 mg tab.

Because of Viagra’s patent expiry, various generic versions are as safe and effective & as the original Viagra [2]. This is the same as modafinil. Generic modafinil & Viagra are similar to their brand-name counterparts but only differ in prices. Generics are super cheap.

Viagra’s mechanism is triggered by its active component, sildenafil, which is a PDE5 inhibitor. It targets the potentially treatable regions of the penile arteries that block satisfactory blood circulation into the penis. Physicians claim that ED is a consequence of the natural body enzyme dubbed PDE5 that eliminates cyclic guanosine monophosphate (cGMP) required to ease & open up the blood vessels to allow in the satisfactory inflow of blood to the penis only when sexually aroused.

After popping, the sildenafil targets the PDE5 & heightens the production of the cGMP. This directs to a protracted & inflexible penile erection necessitated to perform excellently during sexual activity. Differentia penile erections result in comprehensive & fulfilling sex.

Now that modafinil and Viagra work efficaciously, do you need these meds from an online pharmacy? Certainly, ordering generic versions of these meds online is extremely cheap, and you can legally obtain them from a legit & reliable vendor without a prescription. Get Viagra from ViaBestBuys.com and modafinil via ModafinilXL.com. These exceptionally great vendors offer generics at extremely low cost with guaranteed delivery to your address. You can also save more money using vendor-available coupon codes & discounts.

Usage of Modafinil and Viagra Together

As discussed, Viagra and modafinil affect the body differently. But what to expect if using these meds together? Can there be drug-drug interaction? What’s the intensity of interaction?

According to Drugs.com, a drug interactions checker tool, combining Viagra and modafinil has no dangerous effects. Their interaction is minor, implying the mix is safe. Modafinil will augment alertness (including sexual alertness) & lessen sleep. The mixed-use with Viagra isn’t likely to induce any bad effects. Viagra will influence erection, & modafinil will augment alertness. No bad effects.

What are other expected benefits?

Benefits of Mixing Viagra with Modafinil

You may ask: “Can I take Viagra & modafinil together?” Well, searching online, there is no substantial study that investigates the benefits of mixing modafinil and Viagra. However, by observations, there can be some benefits of their mix.

Certainly, drowsiness has been documented as a clinical consequence of the use of sildenafil. Combinations thereof are specifically for augmenting wakefulness, & therapy of sleepiness, jetlag, + sleep disorders linked with excessive sleepiness.

The blend dosage form allows low doses of one or both sildenafil and modafinil to be used, thereby potentially bypassing difficult or even detrimental negative effects [3].

Although there is delayed onset, a mix of low-dose sleeplessness influencing agents, i.e., modafinil, & low-dose PDE5 inhibitor, i.e., sildenafil, is preferably ideal for augmenting wakefulness & the remedy for jetlag, sleepiness, & sleep disorders linked with disproportionate sleepiness.

The mix may also result in fewer negative effects, as peaks & troughs of the level of the med in the bloodstream may indeed be lessened, directing to a more even active ingredient level in the blood over some time. Undoubtedly, such formulations of mixing both meds may also furnish a more prolonged plateau concentration of the med in the blood.

What’s more? According to some quintessences, sildenafil is discharged during or before a period of desired sleeping, while the “smart tab” is discharged at or near or toward the duration of desired wakefulness; alternatively, wherein sildenafil & modafinil are discharged simultaneously or almost simultaneously at, near, or toward the duration of desired wakefulness [3].

Besides, modafinil can unquestionably help eradicate erectile dysfunction issues in some patients who suffered from depression.

Are There Any Negative Effects?

Consider that you shouldn’t self-medicate with modafinil or Viagra. A physician must first assess your health to specify the potential root reason for ED & if it’s most suitable for you to mix with modafinil. Otherwise, if prescribed both meds, administer them according to the prescription. Above all, take note of modafinil & Viagra can induce some negative effects independently.

Negative effects can transpire but not for everyone using these meds. If taken by healthy individuals with impotence only & as per the prescription, negative reactions can certainly be eliminated.

Modafinil with Viagra: Is It Worth the Risk?

Now you’ve known that the mix of modafinil & Viagra is safe, but it doesn’t add any major impact rather than augmented focus, alertness, wakefulness, etc. But is the mix worth the risk? First, understand that modafinil also has some impact on your sex drive.

For instance, if you’re going to encounter coitus after administering modafinil, we wouldn’t counsel that you intend on going more than one round. The “smart tab” commonly hinders male sex drive. Consequently, one round of sexual intercourse may seem marginally delightful, but endeavoring a second round could certainly be a no-go.

The positive use of modafinil for sex is that it remarkably ameliorates your experience due to the extra focus it offers. It heightens focus on the delights of sex — instead of the distractions. In our thought, the added focus you put on the task at hand does indeed present a more delightful experience, but solely if you’re in the exemplary frame of mind, to commence with.

Another thought is that modafinil offers a robust stamina game. Certainly, while you’re presumably to only want one session, you shouldn’t have a predicament expanding your coupling capabilities slightly prolonged. As the “smart tab” impedes sex drive in most men, you may discover yourself enduring longer in bed after popping the “smart drug.”

Now the verdict, based on these pointers, is that a mix of modafinil & Viagra may be beneficial, since modafinil may put you in the mood while Viagra rectifies ED. However, a mix should only be done having consulted with a physician.

References

1. Practical Use and Risk of Modafinil, a Novel Waking Drug. By Dongsoo Kim. Published: February 22, 2012. Ncbi.nlm.nih.gov.
2. Safety of sildenafil citrate: a review of 67 double-blind placebo-controlled trials and the post-marketing safety database. F Giuliano, G Jackson, F Montorsi, A Martin-Morales, and P Raillard. Published: Jan 2010. Ncbi.nlm.nih.gov.
3. Modafinil and sildenafil dosage forms. By Adel Penhasi, Janina Gauchman, Amanda Shauli, Marina Ruderman, and Avi Avramoff. Retrieved: June 18, 2022. Patents.google.com.