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Modvigil 200mg

Modafinil

  1. Alertness

  2. Focus

  3. Energy

  4. Cognition

  5. Motivation

  • Stimulates wakefulness in the brain
  • Promotes mental acuity & processing
  • Enhances focus, motivation & energy
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Modvigil Review – Dosage, Benefits, Side Effects (Beginner’s Guide)

One of the most famous families of cognitive-enhancing drugs is the afinil family.

ย  This family includes several different versions of modafinil,ย armodafinil, andย adrafinil.

The cheapest option within this family is Modvigil, which itself is a generic version of modafinil. Itโ€™s thought to have a milder effect compared to others in its class, which brings several benefits to those looking to use modafinil to boost their productivity.

Here, we discuss Modvigil, how itโ€™s used, how much to take, and how it compares to others in its class.

Letโ€™s get started.

What Is Modvigil?

Modvigil is a generic version of modafinil. Itโ€™s prescribed by doctors for ADD/ADHD, narcolepsy, or shift workers managing sleep disturbances.

Itโ€™s also popular outside of this prescribed range among students, creative professionals, and business owners for its ability to increase focus and productivity.ย Many refer to this drug as a โ€œstudy drugโ€ for this reason.

Several different companies make modafinil.

The brand name of this drug, Provigilยฎ, is made by the American company Cephalon Inc.

Modvigil is a generic and off-brand version of modafinil made by the Indian pharmaceutical company HAB Pharma. Itโ€™s essentially the same chemical as the brand name product but comes at a much lower price.

There are few differences in regards to quality and testing standards between generic drugs and brand name drugs.ย The major difference, however, is the price.

Brand name modafinil (Provigilยฎ) can cost as much as 50 times the off-brand versions likeย Modvigilย orย Modalert.

This is the same with other industries as well, like clothing. A brand name shirt made from one company may be many times more expensive than an otherwise virtually identical shirt made by another company.

You are essentially paying for the companyโ€™s reputation.

modvigil

Where to Buy Modvigil

Due to the legal status of Modvigil, it canโ€™t be bought in stores based out of Europe, the United States, Canada, or Australia.

Modvigil can, however, be bought fromย online vendorsย selling modafinil and armodafinil generics based out of countries like India that donโ€™t classify the drug as a prescription-only medication.

We recommend to buy Modvigil from ModafinilXLย or Afinil for our customers from the US, the UK, Australia & Canada;ย BuyModaย for New Zealand and Thailand; ModafinilXLย and BuyModafinilOnlineย for those who live in the European Union.

Modvigil & Generic Modafinil

Whenever a new drug is invented, the company that developed it will secure a patent. This patent prevents other companies from manufacturing the drug for a certain period (usually 20 years).

Once the patent expires, other companies have the option of making their own generic versions of the drug.

In the case of modafinil, and armodafinil, companies like HAB Pharma and Sun Pharma have stepped up to produce their own versions, which is where we get Modvigil and Modalert.

Whatโ€™s the Difference Between Modvigil and Other Versions of Modafinil?

Although both Modvigil and Modalert contain the same active ingredient, the strength and additives used are different depending on who makes the drug.

HAB Pharma makes both Modvigilย and an armodafinil generic calledย Waklert. This company is an ISO certified contract manufacturing company, as well as the producer of several other generic drugs.

Sun Pharmaceuticals is their main competition in this market. They produce Modalert and Artvigil (an armodafinil generic). Sun Pharmaceuticals is a much largerย international pharmaceutical company primarily operating out of the United States and India.

Both Modvigil and Modalert contain 200 mg of the active ingredient. However, Modvigil is considered the weaker of the two.ย 

This isnโ€™t a bad thing, as some people find 200 mg of Provigil or Modalert too stimulating, and prefer the more subtle effects of Modvigil.

This also makes it more suitable for long-term use than Modalert.

Modvigil is also cheaper than Modalert, making it more accessible to people on a budget.

Updated ย : Modalert is currently not available for sale worldwide. The manufacturer has limited the export of this modafinil generic abroad, now Modalert 200 mg can be purchased if you live in India. Therefore, we suggest considering an excellent premium alternative – ModaXL by HOF Pharmaceuticals. You can order this best-selling nootropic from reliable suppliers all over the world!

Modvigil vs. Other Study Drugs

Other drugs share the same classification and use. Drugs likeย Adderall,ย Ritalin, and Dexedrine are all used to treat ADD/ADHD and narcolepsy. These drugs are also used outside the prescribed uses to improve focus and concentration.

Ritalin is classified chemically as methylphenidate, while Adderall and Dexedrine are classified as amphetamines. These chemicals are very different from the afinil class of compounds despite having similar benefits.

Some of these drugs, like Ritalin and Adderall, are much more stimulating than modafinil.

They can cause notable crashes in energy levels later in the day as the drug wears off. These drugs also tend to produce side effects involved with overstimulation. This can include anxiety, insomnia, poor appetite, teeth grinding, and paranoia.ย Theyโ€™re also more addictive.

Modafinil is much less stimulating on the brain, and users tend to feel a gradual transition back to normal as the modafinil wears off. Itโ€™s also less common to feel side effects on modafinil.

When compared to other drugs of this class, modafinil has been shown to have significantly fewer side effects.ย A recent study found fewer incidences of side effects among participants of a modafinil treatment group compared to an amphetamine (Adderall) group being treated for bipolar disorder [7].

pills

The Legal Status of Modvigil

Modafinil is considered a schedule IV controlled substance in the United States and Australia. This class is defined as substances offering medicinal benefit, but with potential for abuse. These drugs require a doctorโ€™s prescription to purchase.

You can purchase modafinil quite easilyย online, however.ย 

Other countries, such as Canada, Finland, and Sweden have different ways of classifying drugs but places the same limitations on modafinil as the United States and Australia.

Some parts of the world outright ban modafinil.

South Africa, Japan, and China have explicitly criminalized the use of modafinil, punishable by varying lengths of jail sentences and fines if caught with the substance. You cannot buy modafinil from most online vendors in these countries.

The Benefits of Modvigil

Modvigil is a cognitive stimulant. Compared to other stimulants Modvigil is considered to be much more subtle.

Modafinil works through the โ€œorexin systemโ€ in the brain, and increasesย dopamineย and related neurotransmitters likeย norepinephrine.

The orexin system plays a crucial role in regulating our sleep-wake cycles and dopamine, which is involved with emotion, focus, and the reward center responsible for controlling our motivation, routines, and habits.

Modvigil helps users stay focused for longer durations when completing work or study. It helps us require fewer breaks in concentration so that we can accomplish something faster and with more precision. It essentially forces us into a flow state, which many people swear by as the best way to accomplish a job.

This makes Modvigil great for solving writerโ€™s block, finishing tasks more quickly, cramming for a test, or getting through tedious or repetitive work.

Mental Agility

The Benefits of Modvigil include:

  • Improves focus and concentration
  • Boosts the creative thought process
  • Reduces the need to take breaks from work or study tasks
  • Eliminates mental fatigue for several hours
  • Forces the brain into flow states

How Modvigil Works

Modafinil has several different effects on the brain that work together to provide the wakefulness-promoting and cognitive enhancing benefits.

Modvigil increasesย dopamineย [1],ย histamineย [2],ย norepinephrineย [3], andย orexin[4] levels in the brain.

All of which play a part in the process of wakefulness, motivation, and concentration [1].

Modvigil & Dopamine

dopamine structure

Dopamine Molecule

One of dopamineโ€™s main roles is its involvement in the reward center of the brain, which gives us a jolt of pleasure when we do something that benefits our body.

The reason we have this system is to build positive habits that make us want to perform a task again. This happens for activities like eating, exercising, or sex.

We also rely on dopamine for motivation and concentration.ย A region in our brain known as the nucleus accumbens drives this process, which is notoriously high in dopamine.

People suffering from attention deficit disorders like ADHD have been shown to have lower concentrations of dopamine than average [5]. This means that they regularly need to stimulate their brain to trigger the reward center, making it especially difficult to concentrate on or perform just one task at a time.

Dopamine reuptake inhibitors like modafinil and other drugs like Adderall and Ritalin are used to increase dopamine concentrations in the brain to allow the reward center to function more effectively.

This makes it easier for people suffering from attention deficit disorder (ADD) to concentrate.

In healthy individuals, it increases dopamine above and beyond normal levels, providing a potent boost in concentration for several hours while the drug is in effect. Once it wears off, the brain quickly returns to normal levels of dopamine.

Modvigil & Histamine

Histamine Molecule

Histamine Molecule

What do you think of when you hear the word histamine?

Most people go straight to allergies when they think of histamine.

This is because many people reach for the antihistamine drugs when they start to experience classic symptoms of allergies like a runny nose or sneezing.

There are many other uses of histamine in the human body, however.

In the brain, histamine is released from neurons connected to the control center of the brain (the hypothalamus). Itโ€™s used to control stimulation in the brain as part of our circadian rhythm.

Studies have shown that increases in histamine release in the brain result in stimulation and changes to the sleep-wake cycle [6].

Modvigil & Orexin

Orexin Molecule

Orexin Molecule

Orexin is a peptide in the brain involved with the regulation of the sleep-wake cycle, appetite, and neurostimulation [7].

People suffering from narcolepsy often have a dysfunctional orexin system. Narcolepsy is a sleeping disorder where sufferers suddenly go from a waking state to deep sleep.

Modvigil and other versions of modafinil have been shown to increase orexin activation in the brain [4].ย This is likely the mechanism behind most of the wakefulness-promoting benefits of modafinil.

The Negative Effects of Modvigil

Not all the effects of Modvigil or related products are beneficial. Understanding the adverse effects is essential when deciding when and how to take modafinil.

Modvigil (and other versions of modafinil) are so effective at boosting our focus and concentration that in some cases it can work against us.

Sometimes when focusing so intently on one particular task, we can forget about others. It can reduce our interest in social interactions, make us forget to eat or drink, and can leave some of the other tasks we have to do unfinished.

  • Negative effects
    • Stomach discomfortย (most common)
    • Rashesย (rare but can be severe)
    • Headaches
    • Nausea
    • Anxiety
    • Insomnia
    • Dizziness

How Much Does Modvigil Cost?

HAB Pharmaceuticals, the manufacturer of Modvigil, is well-known for its lower cost of medications.

Most suppliers of Modvigil offer different quantities of the drug, which can change the cost of the tablets.

ModafinlXL offers quantities of 10, 20, 30, 50, 100, 200, 300, and 500 tablets per order.

The price will vary from USD $0.38 to USD $2.99 depending on the quantity ordered and payment method used.

This compares to Modalert, which ranges from USD $0.53 to USD $2.99 per tablet.

Provigilยฎ on the other hand, the brand name modafinil, costs as much as USDย $51 per tablet.

If shopping for Modvigil at ModafinilXL use our coupon code: ENJOYMXL10ย to save 10% on your order!

The History of Modvigil

Modafinil is a benzhydryl sulfinyl compound related toย adrafinilย andย armodafinil.

Adrafinil was first discovered in 1974 by a French company called Laboratoire Lafon.

The large American pharmaceutical company Cephalon Inc later purchased Lafon Laboratories, along with the exclusive rights to manufacture adrafinil.

Researchers later learned that adrafinil was metabolized by the liver to produce an inactive metabolite known as modafinilic acid and the active metabolite modafinil.

They then focused on this active metabolite and produced the original version still sold today called Provigilยฎ.

Cephalon Inc held the patent for this substance from 1990 until 2010. Once this patent expired, various other companies began manufacturing their own generic versions of the drug.

HAB Pharma came out with Modvigil shortly after, which has become one of the most popular generic versions to date.

Of course, other companies also produce their own generic versions, including Teva Pharmaceuticals, Shire Pharmaceuticals, Sun Pharmaceuticals, Mylan, Barr, and Ranbaxy.

cephalon

Other generic versions of Modafinil include:

  • Alertec
  • Alertex
  • Carim
  • Mentix
  • Modapro
  • Modasomil
  • Modiodal
  • Provake
  • Resotyl
  • Stavigile
  • Vigia
  • Vigicer
  • Vigil
  • Zalux

Whatโ€™s the Dose of Modvigil?

Each Modvigil tablet contains 200 mg of modafinil.

The tablets come with a convenient crease down the center that allows users to break the pill in half for a 100 mg dose if desired.

The standard dose is one full tablet per day. This can be taken on a daily basis or one at a time to get through particularly demanding tasks. For smaller or more sensitive individuals, the 100 mg dose is often preferred.

It takes about 30 minutes for Modvigil to take effect as itโ€™s absorbed through the small intestines and passes the blood-brain barrier. It then peaks at around the 2โ€“3 hour mark and gradually declines from that point on.

After about 14 hours, most of the drug is cleared from the system through the kidneys.

This can vary depending on the size of the person, the health of the liver and kidneys, and what foods were consumed along with the Modvigil.

Conclusion

Modvigil is a great alternative to other stimulating cognitive enhancers because it has fewer side effects and tends to be less stimulating.

Itโ€™s great for those looking to increase their productivity when trying to cram for an exam, finish a tiring or fatiguing task, or get through creative blocks.

Compared to other forms of modafinil,ย Modvigilย is excellent for those who are looking for something effective but more subtle.ย 

Itโ€™s cheaper than other forms and isnโ€™t likely to cause overstimulation.

We recommend Modvigil for daily use, or for those who are looking for a gentle (but highly effective) cognitive stimulant to finish that tough project, study for that big exam, or finish tedious and mentally tasking activities.

References
  1. Volkow, N. D., Fowler, J. S., Logan, J., Alexoff, D., Zhu, W., Telang, F., โ€ฆ & Hubbard, B. (2009). Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications. Jama, 301(11), 1148-1154.
  2. Ishizuka, T., Sakamoto, Y., Sakurai, T., & Yamatodani, A. (2003). Modafinil increases histamine release in the anterior hypothalamus of rats. Neuroscience letters, 339(2), 143-146.
  3. Madras, B. K., Xie, Z., Lin, Z., Jassen, A., Panas, H., Lynch, L., โ€ฆ & Miller, G. M. (2006). Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates the transporters and trace amine activity in vitro. Journal of Pharmacology and Experimental Therapeutics, 319(2), 561-569.
  4. Scammell, T. E., Estabrooke, I. V., McCarthy, M. T., Chemelli, R. M., Yanagisawa, M., Miller, M. S., & Saper, C. B. (2000). Hypothalamic arousal regions are activated during modafinil-induced wakefulness. Journal of Neuroscience, 20(22), 8620-8628.
  5. Li, D., Sham, P. C., Owen, M. J., & He, L. (2006). Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human molecular genetics, 15(14), 2276-2284.
  6. Brown, R. E., Stevens, D. R., & Haas, H. L. (2001). The physiology of brain histamine. Progress in neurobiology, 63(6), 637-672.
  7. Nasr, S., Wendt, B., & Steiner, K. (2006). Absence of mood switch with and tolerance to modafinil: a replication study from a large private practice. Journal of affective disorders, 95(1), 111-114.
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