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Flmodafinil Dosage Guide: 20-150+ mg Doses

Most nootropic enthusiasts are giving flmodafinil praise, saying it’s faster acting than the famous nootropic modafinil, with extremely fewer negative effects. Although it’s a new research product that’s structurally similar to modafinil, it’s thought to offer longer-lasting effects. Besides, the regular flmodafinil dosage is generally about half of the standard modafinil dosage.

Flmodafinil Dosage Guide

Still, there’s a bit more to it than that. In this flmodafinil dosage guide, we’ll cover all aspects you need to know about this drug including the best starter & intermediate doses, some tips on microdosing, & accurate dosing practices. You’ll also get to know its negative effects & warnings to allow you to dose safely. Besides, you’ll be informed about flmodafinil comparison with modafinil + where you can get this product online. Let’s get started!

What Is Flmodafinil?

In the 1970s, while medical researchers began looking for an efficacious treatment for sleep disorders such as narcolepsy to promote wakefulness, adrafinil appeared during intense research & laboratory tests. Once it is ingested, it metabolizes giving the chemical modafinil. The effect of the latter prompted researchers to term it the classic nootropic used by both healthy populations, particularly students, and sleep-deprived patients to overcome sleepiness, ameliorate cognitive potential, & heighten their concentration [1].

Nonetheless, further studies have given rise to flmodafinil (CRL-40,940) generally known as bisfluoromodafinil & lauflumide [2]. CRL-40,940 is the bisfluoro analog or a derivative of modafinil that is considered to last longer & indeed has higher bioavailability. It’s a robust eugeroic & a weak dopamine reuptake inhibitor.

As stated by its creators, flmodafinil is more efficacious than adrafinil & modafinil, more quickly absorbed, & takes a shorter time for its effects to kick in. It isn’t currently a prescription medicine. It was patented in 2013, & Phase 1 clinical trials have been undertaken since Dec. 2015 [3].

Flmodafinil Benefits

Flmodafinil works as a central nervous system (CNS) stimulant. It betters concentration as well as motivation at the time you necessitate it the most. It also lessens the symptoms of depression. Generally, the drug provides benefits that are similar to those of modafinil.

Flmodafinil Fact Sheet

Listed below are some of the principal advantages linked with the safe use of flmodafinil:

  • heightened productivity, focus, & vigilance: The drug increases the levels of histamine in the brain. It rewards you with extreme focus, intensified productivity, & augmented motivation, making it really easier for you to perform some task or study more successfully;
  • it has no potential for addiction: It’s considered non-addictive & not a precursor molecule for any recognized addictive substances;
  • ameliorated memory, mood, & wellbeing: Similar to modafinil, flmodafinil hinders the reuptake of dopamine [4]. Greater levels of the brain chemical lead to a dramatic boost in short-term memory & mood;
  • it’s 4X more stimulating than modafinil: Flmodafinil has much higher bioavailability, inferring that users can even consume a lower dose of the medication (i.e., 50 mg) & still get the same advantages as they would from administering a much higher dose of modafinil;
  • heightened alertness & individual energy levels: Flmodafinil has the effect of caffeine. It certainly keeps you super alert, active, & energetic after ingestion.

There are several other positive effects flmodafinil gives, just like modafinil. Recall, though, that because it is so brand-new, there is limited research available, especially on its effects & possible benefits, as opposed to modafinil.

Side Effects & Warnings

While there’s no full list of potential negative effects of this product, we can theorize that they may be comparable to those of modafinil. The inventors of flmodafinil, though, assert that it has fewer side effects than modafinil.

So, some of the expected negative effects of flmodafinil are the following:

  • insomnia: If administering this drug late in the day, you may end up being incapable of falling asleep later that night. Note that the earlier you ingest the pill, the greater chance you have of going to sleep at a suitable time. Don’t take it at night unless you are planning on pulling an all-nighter. Besides, drink plenty of water during the daytime to avoid being dehydrated. Certainly, dehydration can negatively influence your sleep [5];
  • headaches: Similar to modafinil, flmodafinil may induce headaches in some individuals. To confirm that, one Redditor reported having a headache after administration of this med [6]. Any health disorder that influences sleep, including bruxism, insomnia, & obstructive sleep apnea, can cause head pain & fatigue. To prevent flmodafinil headaches, always hydrate while on the med. Dehydration can be a primary reason for this unpleasant symptom;
  • anxiety: This is one of the commonest negative effects of cognitive-enhancing compounds, but luckily, many flmodafinil users state that its effects are very minimal. Nonetheless, to some individuals, anxiety induced by this med can exist [7]. To lessen or prevent this side effect, supplement it with gamma-aminobutyric acid (GABA) & L-theanine, take less caffeine & drink more water during flmodafinil intake days, reduce its dosage if it’s too high, and perform some breathing/meditation exercises;
  • gastrointestinal adverse reactions such as heartburn, diarrhea, nausea, gas, & constipation: The symptoms are due to a slow breakdown of the med in the gastrointestinal tract. Flmodafinil boosts norepinephrine concentration in the brain, thus triggering the fight-flight response. In this state, the body diverts energy to more crucial systems, particularly the nervous & muscular systems, to guarantee survival, & the digestive system is forced to be suppressed as a result. Gastrointestinal symptoms can be averted by starting with a very low dose of flmodafinil & slowly increasing it without abusing it. Diet & lifestyle changes play a principal role when using flmodafinil: You need to cut back on consuming fatty foods & exercise more.

There can be other negative effects of flmodafinil. As a warning, this med should not be used by individuals under the age of 18, breastfeeding mothers or pregnant women, people using any psychiatric meds, or those with any underlying health issues. For healthy individuals, flmodafinil doesn’t appear to cause any serious side effects.

Flmodafinil Dosage Guide

Take note that flmodafinil is a comparatively new product, so there is no definitive dosage one can take. However, we’ve decided to create our own flmodafinil dosage guidelines based on modafinil dosage & how to take it, along with all the info we have already learned about flmodafinil.

We already know that flmodafinil is up to 4X more potent than modafinil, & its effects may last longer in the system. Based on this info, we comprehend that the most suitable course of action is to start small. It’s advisable to administer flmodafinil at just one-quarter of the usual modafinil dose. This strategy is especially good for those who are extremely sensitive to stimulants or beginners. In this case, individuals may be able to ingest a dose that’s comparable in strength to a standard dose of modafinil (i.e., one-half of the 200 mg dose), or some may discover that a one-quarter dose, which is comparable to modafinil 50 mg, does the trick.

Take Pill

Overall, it’s a great measure to start with the lowest dose to get the best out of the drug. Now let’s explore the necessary flmodafinil dosage based on various groups in detail.

Standard Flmodafinil (Modafinil) Doses

The usual modafinil dose is 200 mg daily, although some individuals using it for its cognitive or productivity effects opt to take anywhere from 50 mg to 400 mg/day. Here’s a categorization of what these different modafinil doses may be used for:

  • 50 mg/day: This dosage is typically suggested as a starting point for people who are sensitive to nootropics or stimulants. It may be taken 5–6 days/week;
  • 100 mg/day: It’s typical for individuals looking to get through the workday with better efficiency. Some individuals are OK taking this dose strength 2–3 days per week;
  • 200 mg/day: As stated earlier, it’s the standard dose of modafinil. Some individuals report ingesting it 1–3 days/week for getting extra cognitive augmentation;
  • 300 or 400 mg/day: This dosage isn’t advised in the vast majority of cases. Nevertheless, some users may take this dose to stay up for extended consecutive hours.

Certainly, doses up to 400 mg/day of modafinil are indeed well-tolerated, but there is no confirmation that the 400 mg dose confers extra advantage beyond that of the 200 mg/day modafinil dose.

As mentioned earlier, flmodafinil isn’t regulated by the FDA, & it’s still in ongoing clinical trials. Due to this, there is no standard dosing guidance widely available. However, based on the aforementioned dosing patterns, here are our personal dosing guidelines for this medication.

Starter Dosage

For those who haven’t used a similar product or are sensitive to CNS meds, a starter daily dose of 12.5 mg of flmodafinil is recommended. Take note that it is available in 2 different forms (liquid and powder), thus making it easier to split into the lower doses such as 12.5 mg. Besides, flmodafinil tabs in the dose of 25 mg are sold by some online pharmacies, & it’s certainly possible to cut those in half with a good pill splitter. Such a low dose may be used more frequently compared to higher doses, which are advisable to ingest no more than 3 times per week. For individuals who’ve already used modafinil or a similar substance, a starting daily dose of 25 mg of flmodafinil may be suitable, before gradually working up to a dose that fits their needs.

Intermediate Dosage

The intermediate flmodafinil dosage can be anywhere between 50 mg and 100 mg. It is equivalent to 100–200 mg/day of modafinil & seems to be a sweet spot for a majority of nootropic enthusiasts.

Some users can achieve great cognitive effects by splitting the intermediate dosage in half and taking one dose early in the morning and another dose at lunchtime. Splitting a dose in this manner can assist the user to experience more even & consistent focus & energy levels during the day. Like modafinil, it’s recommended to limit this dosage to only 3 days/week.

Dosage 150 mg or More

Certainly, taking a 150 mg/day dose of flmodafinil, which is equivalent to modafinil 300 mg, is not advisable in most cases. Nootropic enthusiasts shouldn’t administer more than 150 mg per day of this medicine because it is still being tested, and the safety and efficacy of its high doses aren’t known.

About Flmodafinil Microdosing

Microdosing is ideal for individuals who are sensitive to nootropics or have a desire to test the cognitive benefits flmodafinil offers with a minimal risk of getting negative effects like insomnia. Indeed, microdosing involves ingesting very low doses of the drug every 4–6 hours or so throughout the workday to achieve steady concentration, mental acuity, & energy.

Some “smart drug” enthusiasts reported experiencing excellent effects from microdosing about 12.5 mg of modafinil, which would be identical to 3–6.25 mg/day of flmodafinil. To get great results, you can take 3 mg to 6.25 mg of the drug every 4 hours during your waking hours (don’t administer it at or close to bedtime). You may try this microdosing plan for 3 days and then take a 3-day break. It’s crucial to notice how your body responds to flmodafinil & make appropriate adjustments in consequent weeks.

Additionally, microdoses of up to 25 mg of flmodafinil, 4 times daily, 3 times per week, should be comparatively safe & risk-free if you are a healthy individual. Nonetheless, you MUST work up to this dosage level gradually until you discover a dose that works great for you.

Flmodafinil Overdose

Little information is available about the possibility of flmodafinil overdose. To avoid any complications, ingest no more than 100 mg/day, 3 times/week (i.e., don’t take more than 300 mg per week). Recall that this drug is now considered a research chemical, but it’s very close to a prescription med — signifying it’s got some awesome power behind it. Indeed, flmodafinil appears to be remarkably stronger than its approved prescription counterpart modafinil. That’s why you should be careful with dosing. An overdose isn’t a good idea since it can be associated with unprecedented negative effects that may necessitate immediate medical attention. It’s prudent to start with a lower dose and increase it subsequently until you get the right dose but with a physician’s intervention.

Accurate Dosing Practices

Certainly, powdered flmodafinil is the easiest to dose precisely. Besides, you can use any kitchen scale to get exceedingly exact dose weights. On the other hand, the liquid form of this compound may also be comparatively straightforward as far as dosing goes. However, you’ll need to make sure you comprehend the ratio of flmodafinil present in the liquid form to do accurate calculations (i.e., how many milligrams of the chemical are present in 5 ml of fluid).

Recommended Dosage Schedule for Beginners Use

Because flmodafinil lasts longer, it almost certainly disrupts your normal sleep at night even when ingested early in the morning after waking up. If you’re a beginner, we certainly recommend starting with a lower dose of 12.5—25 mg. If you are an experienced nootropic user, who’s otherwise healthy, 50 to 150 mg of flmodafinil is best.

If you are trying to use this chemical daily, unless you plan the accurate dose (between 25—50 mg), you should take the lowest possible dose (i.e., 12.5 mg) and plan a dosing schedule (taking it at 7 am & at around 4—5 pm) & make sure that you do something super productive (like studying hard).

Flmodafinil vs Modafinil

Although flmodafinil shares a lot in common with the famous drug modafinil, there are still a few dissimilarities. The major difference between them is that flmodafinil has greater bioavailability than modafinil. Nonetheless, no scientific investigations exist to support this claim at the time of writing this flmodafinil dosage review.

Modafinil Versus Flmodafinil

We know more regarding modafinil, the globe’s first safe “smart tab,” than we do about flmodafinil, but this knowledge gap will certainly come to an end as more data becomes available regarding flmodafinil.

Let’s get some of the truths about flmodafinil versus modafinil:

  • safety: In this regard, we aren’t exactly sure whether flmodafinil is as safe as modafinil. This is because the former lacks rigorous safety analysis. Nonetheless, based on firsthand accounts from research subjects, flmodafinil seems to be relatively safe, & its inventors even suggest that it has fewer negative effects than modafinil;
  • flmodafinil is quicker acting: It gives the same benefits as modafinil while remaining swift-acting. It starts working within just 30 minutes, considerably quicker than modafinil;
  • flmodafinil is considered more potent: Essentially, just 50 mg of this compound is roughly comparable to 100 mg of modafinil in terms of brainpower effects;
  • structure: Both drugs are structurally alike. Flmodafinil is a bisfluoro analog of modafinil, depicting it’s indeed an accurate copy of the latter, with added 2 fluoride units. However, they both function similarly producing identical effects;
  • prescription status: Modafinil is a prescription med & is available for sale with a prescription. However, flmodafinil isn’t currently categorized as a prescription med because it’s still undergoing clinical trials at the moment. However, interested individuals can easily obtain it online as a reference substance;
  • half-life: Flmodafinil has a longer half-life than modafinil. It may stay in your system for longer compared to its prescription counterpart. As more information about flmodafinil comes out, we’ll certainly have a more definitive review of its half-life.

While we can conjecture that flmodafinil works similarly to modafinil due to its almost indistinguishable structure, this isn’t something that we can declare with enough certainty. We’ll indeed wait for more examination to come out before we can get a more influential understanding of how flmodafinil works.

Where to Buy Flmodafinil Online Without Rx?

Since the sale of flmodafinil isn’t restricted like any pharmaceutical substances such as modafinil, it’s easy to order it online — as long as you’re a researcher. Science.bio is the best place to purchase flmodafinil, both powdered and liquid, safely and affordably.

Buy Pills Online

The vendor sells reference substances of the highest quality for life science experimentation. One of the greatest things about Science.bio is that it offers same-day parcel shipping to most countries around the globe. It has exceptional customer service and openly informs about its objectives, goals, & business practices. Each batch of Science.bio’s products including flmodafinil is examined by a reputable third-party lab to guarantee the shopper receives only the highest-quality compound. It also has a 30-day money-back guarantee if a customer isn’t quite satisfied with the ordered product.

Conclusion: Dosing Flmodafinil

Flmodafinil is touted as a robust version of the popular nootropic modafinil. Not only does it start functioning faster after ingestion, but it also offers better focus & mental acuity. Not much can be mentioned about flmodafinil at the moment. Although it seems like an extraordinary nootropic option, we still need to know more about it before we can give any definitive dosage recommendations. That’s the reason why we suggest utmost care when it comes to dosing flmodafinil.


  1. Pharmacokinetic and pharmacodynamic of the cognitive enhancer modafinil: Relevant clinical and forensic aspects. By Ana Sousa & Ricardo Jorge Dinis-Oliveira. Published: January 17, 2020. Tandfonline.com.
  2. CRL-40,940. Retrieved: October 7, 2021. Wikipedia.org.
  3. Lauflumide and the enantiomers thereof, method for preparing same and therapeutic uses thereof. Retrieved: October 7, 2021. Patents.google.com.
  4. A review on modafinil: the characteristics, function, and use in critical care. By Seyed MohammadReza Hashemian & Tayebeh Farhadi. Published: April 4, 2020. Tandfonline.com.
  5. Hydration and Sleep. By Eric Suni. Reviewed by Dr. Abhinav Singh. Updated: January 15, 2021. Sleepfoundation.org.
  6. Newmind – Flmodafinil – Headaches – Anyone Else? By u/fat0n3s. Retrieved: October 7, 2021. Reddit.com.
  7. Flmodafinil from new mind. By u/roellywinklaar. Retrieved: October 7, 2021. Reddit.com.

Modafinil.org is an informational resource about modafinil and other nootropics.