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Phenylpiracetam vs. Modafinil: What Are Differences and Similarities?

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Both drugs, Phenylpiracetam and Modafinil work in the same manner. Though their effects are similar, everyone is different. Phenylpiracetam is a nicer choice for some individuals, while some “smart drug” experts depict that Modafinil is their ultimate choice.

Phenylpiracetam vs Modafinil

Comparing medications is an experience that needs comprehensive research. This guide contains pointers on the uses of both drugs, their similarities, and differences in dosage and side effects, possible interactions with other drugs as well as the ultimate trusted online nootropic vendors in regards to where to get Phenylpiracetam and Modafinil from the best online e-drugstore.

What Are Modafinil Drugs?

Modafinil is a prescription drug used to improve wakefulness in adult patients with diagnosed sleep disorder problems. Modafinil does not cure sleep disorders – it’s a potent remedy to improve sleep problems.

It’s only approved by the Food and Drug Administration (FDA) as a wakefulness-promoting medicine due to excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD).

Doctors extend the use of modafinil beyond its approved prescribed use due to its safety and efficacy. Many physicians are prescribing modafinil “off-label” or “lifestyle” uses for patients exhibiting similar sleep disturbance symptoms. Such conditions can include chronic fatigue syndrome, major depressive disorder, attention deficit hyperactivity disorder (ADD/ADHD), Alzheimer’s disease, depression, multiple sclerosis-induced fatigues, cognitive impairment in schizophrenia, methamphetamine abuse, age-related memory decline, apathy in the elderly, jet-lag, fatigue and other related conditions due to its ability to improve concentration, focus & restore wakefulness among other modafinil benefits.

Safe Modafinil Drugs

With modafinil potency and extended research, it is a drug that comes with other impressive benefits outside sleep-related conditions. Dubbed as the world’s first safe “smart drug”, several people from all walks of life use modafinil off-label due to its cognitive-enhancing effects – as a cognitive-enhancer & productivity booster.

How does it reward with cognitions and productivity? Modafinil effective mechanism of action binds to certain neurotransmitters in the human body that play a major role in decreasing the adequate production of dopamine – an important chemical neurotransmitter in the body that the brain nerves use to effectively communicate with each other. Without effective dopamine concentration in your brain, certain neurotransmitters become imbalanced and can’t communicate as they should and relations with each other are affected leading to certain health conditions such as poor cognition, memory, and sleep, as well as depression, fatigue, among other related problems. Alongside dopamine boosting effects, modafinil also increases the activity of other essential neurotransmitters such as orexin, histamine, & norepinephrine.

By boosting dopamine concentrations in some brain regions, it rewards with effects such as increased blood flow, promoted wakefulness, vigilance, & alertness, and improved energy, memory, focus, & brain executive functioning among other beneficial effects.

Although it can be a cognitive-enhancer drug to students and others, several people – employees, corporate professionals (especially tech industry), astronauts, military personnel and others praised it as the ultimate productivity enhancer that helps keep going on complex tasks that will ultimately boost the intended end productivity. Without a doubt, modafinil is a powerhouse when it comes to enhancing mental focus, concentration & thinking.

In healthy individuals taking modafinil, it effectively improves planning and accuracy on certain cognitive tasks. Count this as another added benefit. It’s the same way as to how amphetamine and methylphenidate also enhance the performance of healthy individuals in certain cognitive tasks [1],[2].

Modafinil can also help boost your productivity. Experts secretly use it for potent effects such as increased concentration and unlimited energy. An increasing number of healthy entrepreneurs are safely using this “smart drug” to give themselves a competitive edge or mental acuity and wakefulness during long days and late nights running a startup into a fruitful state. And as an entrepreneur, you become an active corporate mortician that will peacefully bury someone’s great startup due to low productivity and competitive outrun. Effects of popping a “smart pill” like modafinil include increased productivity, attention, motivation, mental clarity, and cognitive abilities. Adderall and Ritalin have been known to provide similar effects like Modafinil – a “smart drug” being marketed as non-habit forming – making it the #1 piping-hot commodity [3]. How about Phenylpiracetam? Can you replace it with Modafinil?

What Is Phenylpiracetam?

With the same effects as modafinil, it’s not a surprise to consider that phenylpiracetam is one of the most popular brain stimulants that enhances cognition, mood, memory and physical functioning of the human body.

As you associate popular nootropics with students taking it to stay up all night for exams or powerful business people trying to boost their productivity, what can you associate phenylpiracetam with? It can be just like modafinil, but this drug has gained notoriety because of enhanced physical function.

Phenylpiracetam Drug

For example, in 2006 Russian Olympic biathlete Olga Pyleleva was stripped of a silver medal just because of taking Carphedon stimulant drug. Also, Anton Reshetnikov, a Russian cyclist, was suspended in 2007 from the International Cycling Union just because of the use of Carphedon and Furosemide [4].

Carphone is another version of phenylpiracetam medicine. It differs from Piracetam due to the addition of a phenyl drug group. The phenyl class of drugs enables Phenylpiracetam to effectively cross the blood-brain barrier much more easily than Piracetam does. It can be said it’s an advanced drug of Piracetam. Phenylpiracetam is more bioavailable and has a longer half-life than Piracetam. Because of these Phenylpiracetam qualities, it’s estimated to be between 20 – 60 times stronger than Piracetam.

Developed in Russia in early 1980, this medicine was used to increase cosmonaut’s vigilance and productivity on spaceships [5]. However, today it’s marketed in Russia as a prescription medicine with the name Nootropil.

Now, since this drug is common in sports and other productivity fields, how does it work? What are its benefits? Phenylpiracetam enhances both mood and cognition. Although it’s highly effective and safe, it acts as a mild stimulant and, uniquely, it powerfully functions to enhance physical endurance and resistance to cold. As a result, it’s used to improve physical as well as mental performance, just like what modafinil does. Consequently, with its added effects, bodybuilders sometimes also use it before working out [6].

As a cognitive-enhancer with rewarding effects, Phenylpiracetam works similarly to other racetams – improving memory, focus, and concentration. Also, as a highly potent mood enhancer, it lowers depression and anxiety just like Aniracetam.

Certainly, Phenylpiracetam effectively enhances individual memory function and acts as an antidepressant [5]. It has a neuroprotective effect that’s stronger than that of Piracetam. It effectively functions by increasing blood flow to the brain, enabling the retention of cognitive functions at a higher degree and increased survival rate.

Research shows that patients with encephalopathy if given Phenylpiracetam medication, improved their memory, motor coordination, attention, reduced anxiety, and depression, decreased limb and facial muscle weakness. A higher percentage of patients became more active [7]. Also, this drug reduces seizures in mice (according to research) and, when combined with antiepileptic drugs, it substantially decreases seizure activity in epileptic patients [8].

As a stimulant, this drug is said to resemble Adderall in its effects and benefits. However, it does not have serious negative effects.

How does it work? It works just like what modafinil functions in affecting human neurotransmitters in the brain. Phenylpiracetam affects acetylcholine, glutamate, dopamine, GABA-A, and serotonin receptors [9]. Impressively, people use this medication due to its effects on certain body chemical substances that promote cognition, memory, mood, and concentration.

Although Phenylpiracetam has limited studies in Russia, it remains a potent medicine that has proven to be effective in restoring neurological functions, aid in lowering depression, and at a considerate level help to boost cognitive functions in the organic brain lesions individuals (any type of abnormal tissue in or on brain tissue).

Compare Modafinil and Phenylpiracetam

What’s your phenylpiracetam vs. modafinil experience? When it comes to how these drugs enhance cognition, memory, and productivity, subjectively, the effects of these drugs are the same. Those who have taken both medicines can notice that Phenylpiracetam is more subtle, but due to the same mechanism of action – as to how it affects certain brain neurotransmitters, its effects are very similar.

Phenylpiracetam and Modafinil

Phenylpiracetam is more distinct from modafinil as its effects come on much quicker. It can be hard to choose the best cognitive enhancer. The key to getting the best results with phenylpiracetam is to be consistent and find the best dose strength that works for you. Start with a low dose and consistently increase. This can take a long time, but once you get it, the benefits become golden. Phenylpiracetam is a nice pick for a certain group of people and it’s way cheaper than modafinil. Read reviewers on Reddit about both drugs and make your conclusions [10].

How can we compare modafinil and phenylpiracetam? There are various reasons why people use the nootropic stacks alongside modafinil or phenylpiracetam. Some of the reason for taking a stack of certain medication can be:

  • to boost resistance to the cold;
  • to aid long-term memory recall & formation;
  • to minimize sleep problems;
  • to fight the depression;
  • for boosting problem-solving skills (as brainpower & cognitive enhancer medicine).

Modafinil is in the list of banned products for use during competition by athletes by the World Anti-Doping Agency (WADA), as well as, Phenylpiracetam. Another considerable similarity between the two medicines is that they both expose the user to almost the same negative effects which are considered minor when the user is healthy and takes the right dosages.

Drug Modafinil Phenylpiracetam
What form does this drug come in? oral tablet powder & capsule
How to take it?
  • take once daily (in 24 hours) for treating sleep disorder conditions;
  • take as needed for productivity and cognitive-enhancing effects (45 minutes to an hour for a planned task).
take 2-3 times per day (totaling a daily range of 200-600 mg)
What is this drug used for?
  • improve wakefulness in people with narcolepsy, OSA, or SWD and other related conditions;
  • as a cognitive enhancer.
  • prescribed as a general stimulant or to increase tolerance to extreme temperatures and stress;
  • treatment of Parkinson’s disease and others [11].
What is it also known as? modafinil (Provigil®), armodafinil (Nuvigil®) and generics phenotropil, carphedon
What is it good for?
  • mental focus;
  • energy;
  • agility;
  • motivation;
  • cognition.
  • energy;
  • memory;
  • physical performance.
With what does it stack well?
  • Noopept;
  • Piracetam;
  • choline;
  • fish oil;
  • Ashwagandha;
  • Phenibut;
  • Phenylpiracetam;
  • Bacopa;
  • L-Theanine, etc.
  • Alpha GPC;
  • CDP Choline;
  • Piracetam;
  • Centrophenoxine;
  • Sulbutiamine, etc.
What strengths does this drug come in? 100-200 mg
  • 100–250 mg (capsules);
  • 5 g, 10 g, 25 g (powder).
What instructions should you follow?
  • take with or without food;
  • after a fat meal may result in a little longer time to start working;
  • it’s best to avoid alcohol.
  • taken with or without food;
  • after a fat meal may result in a little longer time to start working;
  • avoid mixing it with alcohol.
What is the half-life of this drug? 15 hours 3–5 hours
Is it effective? excellent good
Is this a controlled substance? yes
  • not included in the schedules to the CDSA and is not a controlled substance;
  • not scheduled by the U.S. Food and Drug Administration.
Is there a risk of withdrawal with this drug? no no
Does this drug have the potential for misuse? yes, prohibited by the WADA [12] yes, prohibited by the WADA
What is the typical length of treatment? long-term treatment short-term treatment

You can consider using either of the two since they will all deliver similar results. When using both drugs stick to your medical specialist’s instructions for quality positive effects.

Where to Buy These Medications Online Without Rx?

Notably, racetams are some of the best-researched, the oldest cognitive-enhancing drugs and they have very few side effects. Phenylpiracetam gives you quite a lot of energy – improves the processes of learning and storing conditional skills [13]. This effect is the same as modafinil benefits.

Choose an Online Pharmacy

If thinking of where you can source a “smart drug,” we recommend the following best e-pharmacies that exist to provide you with quality medications sourced from approved manufacturers.

ModafinilXL does what it promises. Reviews state more – a trusted modafinil vendor offering genuine nootropics at an extremely lower cost. No price hiking from this “smart drug” vendor. Every buyer is eligible for discounts, offers, and coupons that help lower the total “smart drug” cost of modafinil and armodafinil.

Most importantly, a modafinil buyer can get a 20% discount just by using Bitcoin as payment. It also has other payment options. This vendor offers ultra-fast shipping to most parts of the world – except not to a very few listed destinations.

Shopping from this vendor is awesome. Get free Standard shipping for orders of $130 and above, if choosing the Express Mail Service (EMS) as your preferred delivery option, it’s free for orders above $180. Interestingly, a customer gets a $30 coupon just for leaving a review and $25 off for a returning buyer.

We recommend buying modafinil from ModafinilXL for customers who live in the US, the UK, and Australia. This vendor delivery is 100% guaranteed. But, in rare cases, if your parcel gets stuck in customs or lost, you get free reshipment or a full refund. It’s the best place to buy “smart drugs” online. Ship with confidence and enjoy this highly secured e-pharmacy as it uses an SSL certificate for shopping and payment protection.

BuyModa is best for buyers from Canada. Its product payment includes a 10% discount for checking out using Bitcoin. This best and trusted vendor offers free shipping with tracking numbers on all of the buyer medications with the exceptions of a few countries in the European Union and Canada. For countries not explicitly covered by this vendor, it recommends using for forwarding services.

Its orders are typically processed within 24 business-day-hours after your order and it can take between 3-30 days to arrive, depending on your location. As a “smart drug” vendor that’s preferred by many reviewers, it offers payments via Visa, MasterCard, American Express, and PayPal.

BuyModa offers a 100% satisfaction guarantee. Returning customers receive a bonus of 20% of the amount of paid tablets on each consecutive order. If your parcel gets stuck in customs, this vendor reships your order. If they reship and experience another unsuccessful delivery (twice), they will refund you in full amount. Definitely, without a doubt, this is the ultimate “smart drug” vendor of modafinil and armodafinil.

Afinil is another great nootropics vendor including other medications for different health conditions including cancer, HIV, diabetes, weight loss, and others as depicted in its category. This is a sure sign that this vendor does exactly what it promises.

Its products are sourced from approved manufacturers and it offers fast delivery. To covered countries, it offers reshipment or a full refund. Nonetheless, due to certain countries with strict customs and drug importation laws, it doesn’t offer a refund or reshipment. Check its list if your country is eligible for successful delivery, free reshipment or refund if it gets stuck in customs.

Read more about HighStreetPharma here.

For countries not explicitly covered by this vendor, it highly recommends using Skypax for forwarding services.

Among other impressive benefits, this vendor offers 24% crypto discount & 30% extra pills for nootropic families of drugs. It also offers free Express shipping worldwide for nootropics orders.

The best vendor to consider also is Eufinil – the first and only modafinil vendor that is based in Europe. This means you do not have much to worry about “smart drug” shipment if you live within the EU territories. It ships well to most the EU countries and unlike importing generic medicines outside the EU, things are smooth when you use this vendor.

With this vendor, it guarantees a lightning-quick delivery time. That’s faster than you’d order from another e-pharmacy located outside the EU. Eufinil also offers a full money-back guarantee on any failed order delivery. However, being a great and reliable e-pharmacy of nootropics including modafinil and armodafinil pills, you only have to pay for your products using Bitcoin. Interestingly, this is the safest way of making online purchases and still, this vendor is a solid choice indeed.

This is a shortlist of great nootropic vendors. The ultimate choice of the best vendor depends on your location, drug pricing, and delivery time.

How about Phenylpiracetam? Where can you get it? Unfortunately, most nootropic vendors don’t offer this type of medication. Due to this reason, we recommended Amazon as the best alternative source or other pharmacies, but remember to get trusted and legit one that offers genuine medications.

Dosage of Modafinil vs Phenylpiracetam

As a safe medicine, apart from using it to promote wakefulness – as a sleep disorder prescription, healthy individuals including students, employees, and professionals among others just want to achieve a competitive edge by using this medicine. Modafinil can be used by anyone, who wishes to stay awake, work late, enhance their cognitive reactions, or brighten their moods and beat depression and stress among other nootropic effects [14].

Modafinil Dose

Depending on the purpose of treatment, doctors recommend Modafinil 200 mg to be taken for:

  • narcolepsy & OSA: taken once a day in the morning;
  • SWD: taken approx. 1 hour before the start of the work shift;
  • other sleep disorder conditions, for cognitive enhancement or productivity tasks.

Modafinil is common in workplaces. Since its onset of action is in 2-3 hours, it’s administered an hour before a planned productivity task or for cognitive power to achieve more during complex tasks.

Phenylpiracetam is taken at a dosage of 100-200 mg acutely. It should be taken 2-3 times per day (totaling a daily range of 200-600 mg). The lower range seems very effective for most people, but the use of optimal dosage is not yet known.

Because of its strength, as a starter, it’s recommended that you begin with no more than 100 mg of phenylpiracetam a day. No more than 300 mg should be necessary. Due to its half-life, you may consider dividing the dosage into the early morning and early afternoon doses. Don’t take Phenylpiracetam later in the day, as its stimulant effect can potentially cause insomnia.

It’s highly recommended not to administer a nootropic drug without consulting with a doctor. Dosage should be taken at the right time as prescribed by a doctor including dose adjustment depending on your health.

Is There a Difference in Side Effects?

Are there differences between Phenylpiracetam versus Modafinil in negative effects? Both drugs exhibit the same characteristics – cognitive benefits, promoting wakefulness, as well as having nearly the same negative effects.

Their side effects include headaches, insomnia, dry mouth, and nausea. All the adverse effects are temporary, but in case they are prolonged – seek medical attention immediately.

Note that modafinil’s negative effects can last for a few days, hours, or minutes and fade away with continual use of medication. Its side effects are normally classified into the following groups:

  • common;
  • rare;
  • and reactions to overdose or allergy [15].

Some of the common side effects include:

  • nausea;
  • dizziness;
  • headaches;
  • insomnia and others.

Rare cases users may experience:

  • depression;
  • anxiety;
  • hallucinations.

Taking modafinil may cause allergic reactions to an individual such as severe rashes. Also, modafinil is likely to cause dizziness or blurred vision. Don’t drive or operate heavy machinery after taking a nootropic.

Side Effects of Modafinil

Phenylpiracetam users have reported, such symptoms, as:

  • psychomotor agitation;
  • dysphoria;
  • tiredness;
  • dizziness;
  • memory loss;
  • diarrhea.

It’s highly recommended not to stop the nootropic medication suddenly – it can contribute to withdrawal symptoms and other effects. Before using any drug, you should consult a doctor.

Interaction with Other Meds, Food and Alcohol

Modafinil and Phenylpiracetam are not for everyone. They work best on individuals who are healthy without any health complications. As a precaution, always follow the instructions given in the drug leaflet with additional advice from a doctor and do not mix drugs.

Modafinil notable drug interaction includes:

  • CYP2C19 & CYP3A4/5 substrates;
  • warfarin;
  • illegal drugs (such as MDMA or Ecstasy, methamphetamine);
  • monoamine oxidase inhibitors;
  • birth control medications and others.

This is not a full list [16]. When using modafinil, be aware of some health conditions including:

  • heart issues;
  • chest, liver & kidney pain;
  • high blood pressure;
  • mental/mood disorders (such as mania, depression, psychosis), etc.

It may cause health problems including moderate or major health conditions due to side effects. Using grapefruits/juice or mixing with alcohol can cause some unprecedented side effects [17].

This is not a comprehensive list [18]. Being safe means not to mix certain stimulants with other drugs. At best, avoid mixing medicine. Where in doubt, ask your medical specialist for guidance. Drinking alcohol on stimulants is risky – it may cause a high risk of liver damage and increased dehydration or other unprecedented side effects.

Phenylpiracetam moderate interacts with:

  • cilostazol;
  • clopidogrel;
  • dipyridamole;
  • eptifibatide;
  • prasugrel;
  • ticlopidine;
  • tirofiban.

Phenylpiracetam mild interacts with:

  • levothyroxine;
  • liothyronine;
  • thyroid desiccated [19].

Note, it’s not a full list. You should consult your medical specialist before taking these pills.


Which is the ultimate medicine for your desired purpose? Phenylpiracetam is 10 times more powerful than Piracetam and kicks in much faster. This effect allows even small amounts of it to provide a mighty boost to cognition and productivity.

From problem-solving to concentration, and from motivation to memory, Phenylpiracetam provides broad-action enhancement across a range of cognitive attributes. This is the same as Modafinil – dubbed as the world’s first safe “smart drug”. It’s a safe drug that millions of people use to promote wakefulness, improve productivity and impressively achieve more in cognitive tasks – Modafinil is a powerhouse when it comes to cognitive-enhancing effects.


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  2. Translational approaches to frontostriatal dysfunction in attention-deficit/hyperactivity disorder using a computerized neuropsychological battery. Published: June 2011.
  3. A Look at Modafinil and Getting an Entrepreneurial Edge, the Natural Way. Published: May 7, 2013.
  4. Phenylpiracetam: A Powerful Racetam with Unique Properties. Posted: Jule 24, 2014.
  5. Investigation into Stereoselective Pharmacological Activity of Phenotropil. Published: June 20, 2011.
  6. Determination of carphedon in human urine by solid-phase microextraction using capillary gas chromatography with nitrogen–phosphorus detection. Retrieved: April 9, 2020.
  7. The phenotropil treatment of the consequences of brain organic lesions. Published: 2005.
  8. Complex treatment of epilepsy with phenotropil. Published: Jan 2007.
  9. The effects of scopolamine and the nootropic drug phenotropil on rat brain neurotransmitter receptors during testing of the conditioned passive avoidance task. Published: June 8, 2011.
  10. Phenylpiracetam vs modafinil experience |r/Nootropics. Retrieved: April 9, 2020.
  11. Phenylpiracetam. Retrieved: April 9, 2020.
  12. Prohibited In-Competition | Stimulants. Retrieved: April 9, 2020.
  13. Role of functional state of neuronal mitochondria of cerebral cortex in mechanisms of nootropic activity of neuroprotectors in rats with alloxan hyperglycemia. Published: 2015.
  14. Practical Use and Risk of Modafinil, a Novel Waking Drug. Published: Feb 22, 2012.
  15. Modafinil Side Effects by Likelihood and Severity. Retrieved: April 9, 2020.
  16. PROVIGIL® (modafinil) Tablets [C-IV] (PDF). Retrieved: April 9, 2020.
  17. Mixing Modafinil With Alcohol. Retrieved: April 9, 2020.
  18. Provigil (modafinil) Drug Interactions. Retrieved: April 9, 2020.
  19. What is Piracetam and how does it work?