Nootropics, also known as “smart drugs” or cognitive enhancers, have gained significant popularity for their potential to enhance cognitive functions such as focus, memory, and mental acuity. Modafinil and armodafinil are two prominent nootropics that have been widely used and researched. They are primarily prescribed to individuals with sleep-related disorders but have also found favor among students, professionals, and individuals seeking cognitive enhancement and an edge.
In this comprehensive guide, we delve into the details of ModaXL vs. Modvigil vs. ArmodaXL vs. Artvigil, four popular meds in the modafinil and armodafinil family. Which is better? Here, we compare their characteristics, benefits, differences, and negative effects. Additionally, we explore the legality of these drugs and provide a list of reputable online pharmacies where they can be purchased with or without a prescription. Let’s dive in.
Which Nootropic Should I Buy?
Choosing the right nootropic can be a daunting task, especially with the multitude of options available in the market. Today, nootropics are widely used for cognitive enhancement, motivation, and sleep disorders. Their popularity has grown significantly, with millions of people seeking their benefits. If you’re considering diving into the world of nootropics but find yourself wondering, “Which one should I buy?” – fret not! Below is a summary of popular choices in the modafinil and armodafinil generics categories. By understanding their unique characteristics and benefits, you’ll be better equipped to make an informed decision. Let’s explore each of these drugs in more detail:
ModaXL
As the current best-selling modafinil-based nootropic in most online pharmacies, ModaXL offers a safe and effective option with a relatively low potential for side effects. Notably, it stands out for its higher potency and faster onset of effects compared to other generic modafinil brands.
Modvigil
Ideal for those new to modafinil, Modvigil provides excellent value for money. It is a safe, well-tolerated option that many users find effective, making it a popular choice for beginners. It provides cognitive enhancement and wakefulness-promoting effects without overwhelming intensity & allows newcomers to experience the benefits of modafinil gradually, making it a suitable option for those new to nootropics.
ArmodaXL
Similar to ModaXL but based on armodafinil, ArmodaXL is one of the top-selling armodafinil-based nootropics in online pharmacies. It offers greater potency and faster onset of effects compared to several other armodafinil generics. This makes it a suitable choice for individuals requiring prolonged periods of concentration. It also boasts a good safety profile and high tolerability.
Artvigil
Artvigil is a cost-effective armodafinil variant that offers slightly milder effects compared to other options. It is a great choice for individuals looking to maintain a restful night’s sleep while still enjoying the cognitive enhancement benefits of a nootropic. Artvigil is known for its safety and good tolerability, making it a reliable option for those seeking a well-rounded experience.
When deciding which nootropic to purchase, it’s important to consider your specific needs, preferences, and desired effects. Additionally, consulting with a healthcare professional is crucial, especially if you have underlying health conditions or take other medications. By understanding the characteristics and benefits of ModaXL, Modvigil, ArmodaXL, and Artvigil, you can make an informed decision on which nootropic is best suited to your requirements.
Compare Modafinil vs. Armodafinil
Before giving their comparison, here is a definitive view of these drugs. Modafinil is classified as a wakefulness-promoting medication and is available in 100 mg and 200 mg dose strengths. It is considered safe, well-tolerated, and has a low risk of addiction. Researchers from Oxford and Harvard Universities have referred to it as the “world’s first safe ‘smart drug'” due to its minimal side effects and low potential for dependence [1][2].
Similarly, armodafinil also belongs to the wakefulness-promoting medication class and is available in 50 mg, 150 mg, 200 mg, and 250 mg dose strengths. It is safe, well-tolerated, and has a low potential for addiction. However, it is more potent than modafinil, with studies suggesting it is 1.33 times stronger. This means that a 150 mg dose of armodafinil has comparable effects to a 200 mg dose of modafinil [3][4]. Though this in no way disparages modafinil’s use.
Both drugs are effective but cater to different individuals. Armodafinil is ideal for individuals with mentally demanding jobs that require prolonged concentration, thanks to its stronger effects. On the other hand, modafinil is a milder option, making it a suitable starting point for newcomers to nootropics.
It is important to note that both modafinil and armodafinil are classified as Schedule IV controlled substances. Therefore, it is recommended to consult a doctor before initiating treatment with either of these medications.
In summary, if you are considering trying nootropics, it is advisable to start with modafinil. If modafinil does not produce the desired effects or is ineffective for you, then you can consider using armodafinil as an alternative. Starting with modafinil allows you to gauge its impact on cognition and wakefulness before exploring the potentially stronger effects of armodafinil.
What Is Modafinil?
Modafinil, a remarkable medication, stands out for its originality and versatility. Originally developed by French neurophysiologist Professor Michel Jouvet and Lafon Laboratories, it was primarily designed as an experimental treatment for narcolepsy in 1986. However, its unique properties and benefits quickly garnered attention beyond its intended use.
The United States Food and Drug Administration (FDA) recognized the efficacy and safety of modafinil in treating narcolepsy and approved it for this indication in 1998. Subsequently, in 2003, the FDA expanded its approval to include two additional sleep disorders: obstructive sleep apnea (OSA) and shift work sleep disorder (SWSD) [5]. These official approvals highlight modafinil’s effectiveness in promoting wakefulness and addressing sleep-related conditions.
Interestingly, modafinil also gained recognition for its cognitive-enhancing properties. Although not officially approved by the FDA for this purpose, numerous studies and anecdotal reports suggest that modafinil can improve cognitive functions such as alertness, focus, memory, motivation, planning & decision-making skills, overcoming procrastination, and mental processing speed. As a result, many individuals, including students, professionals, and those seeking improved productivity & edge, have turned to modafinil as a cognitive enhancer. It is important to note that while modafinil has demonstrated positive effects, it should be used responsibly and under medical supervision.
About Modafinil Generics
Modafinil went generic after the expiration of its patent [6]. Numerous pharmaceutical companies, especially from India, have since developed their own versions. However, Modvigil, ModaXL, and Modalert emerge as some of the most widely used. In this section, we delve into these meds, discussing their respective manufacturers, dosages, potential side effects, and interactions.
ModaXL Review
ModaXL is a relatively new generic version of modafinil, manufactured by HOF Pharmaceuticals, an Indian-based company known for producing high-quality medications. It is available in 100 mg and 200 mg strengths, similar to its brand-name counterpart.
Compared to other generics like Modvigil and Modalert, ModaXL offers several advantages. It has a peak effect that is approximately 40% stronger and a slightly faster onset of effects due to its higher absorption rate. The medication is packaged in special aluminum packaging, ensuring long-lasting freshness with an expiration period of 3 years.
While ModaXL is generally safe and well-tolerated, it’s not without potential negative effects, although they are rare and usually resolve on their own. Common negative effects include upset stomach, nausea, runny nose, headache, insomnia, dizziness, & drowsiness. Nonetheless, more serious adverse effects can occur in cases of overdose or misuse, such as ringing in the ears, depression, hallucinations, mood swings, & confusion, which may demand immediate medical attention.
It is important to be cautious of potential drug interactions while using modafinil or related meds like ModaXL & Modvigil. These substances can interact negatively with alcohol, certain medications, food, or herbs, affecting their efficacy or increasing the risk of side effects. ModaXL specifically interacts with medications such as clopidogrel, deflazacort, rifampin/Rifadin, bosutinib, antifungal meds like itraconazole/Sporanox or ketoconazole/Nizoral, sedatives like midazolam/Versed, triazolam/Halcion, diazepam/Valium, and street drugs like poppers (methamphetamine).
To ensure safety and effectiveness, it’s crucial to consult a healthcare professional or doctor before initiating treatment with any medication, including ModaXL.
Modvigil Review
Modvigil, a widely recognized generic brand of modafinil, was previously a top-selling product in numerous online pharmacies until the emergence of ModaXL. Manufactured by HAB Pharma, it is available in two strengths: 100 mg and 200 mg. Sun Pharmaceuticals holds a prominent position as one of the largest pharmaceutical companies in India. In the United States, it’s recognized as one of the leading generic pharmaceutical firms, ranking among the top ten. It has particularly established itself as the second-highest-ranked company in the generic dermatology market.
Modvigil is an effective treatment option for sleep disorders. Additionally, it offers notable cognitive-enhancing benefits.
Compared to ModaXL, Modvigil is priced lower, likely due to its slightly slower onset of action and milder effects. In addition to its effectiveness in treating sleep disorders and its cognitive-enhancing benefits, Modvigil has gained popularity for its affordability compared to other modafinil generics. This makes it an attractive choice for individuals seeking the benefits of modafinil without breaking the bank.
Key advantages of Modvigil include extended periods of heightened focus for over 10 hours, improved memory, increased motivation, enhanced alertness, and faster mental processing speed. When used correctly, Modvigil is generally safe and doesn’t typically cause significant discomfort. As it shares the same active ingredient as ModaXL, its side effects, and potential interactions are similar. It is important to note that modafinil drugs are contraindicated for pregnant women, breastfeeding mothers, and individuals under the age of 17.
What Is Armodafinil?
Armodafinil is a medication that belongs to the class of drugs known as wakefulness-promoting agents. It is the R-enantiomer of modafinil, which means it is a more purified form of the active ingredient found in modafinil. The original formulation of armodafinil was developed by Cephalon Inc., a pharmaceutical company that is now a part of Teva Pharmaceutical Industries. In 2007, the FDA approved it to treat narcolepsy, SWSD, and OSA.
Armodafinil is highly regarded for its potency and effectiveness. It is considered to be more powerful than modafinil due to its increased concentration of the active compound. Studies have shown that armodafinil is approximately 1.33 times stronger than racemic modafinil, which is a mixture of both the R and S enantiomers.
The reputation of armodafinil stems from its ability to promote wakefulness and improve cognitive function. It has gained popularity beyond its approved uses as a cognitive enhancer, with individuals seeking its benefits in terms of increased alertness, focus, and productivity.
Due to its potency and longer duration of action, armodafinil is often preferred by individuals who require sustained wakefulness and mental acuity for extended periods. However, it is worth noting that the choice between armodafinil and modafinil depends on individual needs and responses, and consulting a healthcare professional is advisable to determine the most suitable option.
About Armodafinil Generics
Armodafinil, originally marketed as Nuvigil by Cephalon, now has several generic versions available at a lower cost while providing similar benefits [7]. Some notable generic options include Artvigil, ArmodaXL, and Armodavinil. These generics have gained popularity in the market for their affordability and comparable effectiveness to brand-name medication. Let’s explore two of these popular generic versions in more detail.
ArmodaXL Review
ArmodaXL, a relatively new armodafinil-based medication, has gained attention in the market. Manufactured by HOF Pharmaceuticals, it is commonly available in 150 mg strength. Compared to other armodafinil generics like Artvigil, ArmodaXL offers improved features. Similar to ModaXL, its modafinil-based counterpart, ArmodaXL provides stronger effects and a faster onset of action. Its peak effect is approx. 30% stronger, and it has a higher absorption rate of 5%.
While ArmodaXL has a low risk of side effects, there is a possibility of experiencing mild symptoms such as headaches, nausea, dizziness, insomnia, and drowsiness, particularly in first-time users. However, these side effects tend to diminish as the body adjusts to the medication and usually do not require treatment. It is important to note that more serious adverse effects, including depression, mood swings, and hallucinations, can occur if the drug is used improperly. If any of these severe adverse effects manifest, it is crucial to seek immediate medical attention, as they can pose a risk to one’s well-being.
Like ModaXL, ArmodaXL may interact negatively with alcohol, grapefruit, grapefruit juice, and certain meds such as clonazepam, omeprazole, gabapentin, Lexapro (escitalopram), Levothyroxine, and Cymbalta (duloxetine) [8]. Combining alcohol with the drug can lead to blackouts, while grapefruit and grapefruit juice can increase the likelihood of adverse effects. To optimize the benefits of ArmodaXL, it is advised to avoid these combinations.
When used correctly, this medication is highly likely to be effective for individuals seeking heightened cognitive enhancements.
Artvigil Review
Artvigil, another well-known generic version of Nuvigil, is manufactured by HAB Pharma, a reputable and reliable pharma company based in India. It contains pure armodafinil as its active ingredient, ensuring that it provides the same benefits as the brand-name medication and exhibits similar side effects and interactions. Possible side effects of Artvigil may include insomnia, nausea, runny nose, dizziness, and drowsiness.
Use this med correctly to minimize the risk of severe side effects. In rare cases, incorrect usage of Artvigil can lead to serious adverse effects such as mood swings, hallucinations, impaired or complete loss of vision in one or both eyes, ringing in the ears, and more. If any of these adverse effects occur, seek immediate medical attention, as they can pose a life-threatening situation if left unaddressed.
Artvigil shares the same drug and substance interactions as ArmodaXL, as they both contain the identical active ingredient, armodafinil. Therefore, it is important to be aware of potential interactions with other medications and substances when using Artvigil.
Where to Buy Generic Modafinil and Armodafinil Online?
Ultimately, modafinil & armodafinil are legal in various countries across the globe, including the United Kingdom, Australia, the United States, & New Zealand. However, in most countries, they are categorized as Schedule IV controlled substances, which means they require a prescription for legal acquisition. In Russia, it’s a Schedule II controlled substance; in mainland China, the “smart drug” is classified as a Class I psychotropic drug; in Canada, modafinil isn’t listed in the Controlled Drugs and Substances Act, but it is a Schedule F prescription drug. While it is possible to buy and use these drugs for personal use with a prescription, obtaining them for cognitive enhancement purposes can be challenging.
To circumvent this issue, individuals seeking these “smart drugs” often turn to online pharmacies that operate in countries with more lenient regulations surrounding the use, sale, and purchase of modafinil and armodafinil. It’s important to note that purchasing drugs online carries risks, as there are many vendors who sell counterfeit medications. To assist you in finding reliable sources, we have compiled a list of reputable e-pharmacies known for delivering high-quality modafinil- and armodafinil-based drugs to customers. Some of these trusted online pharmacies include Afinil.com, ModafinilXL, BuyModa, BuyModafinilOnline, BuyArmodafinil, FreeModafinil, and HighStreetPharma.
The following table presents the unique features associated with each of these pharmacies to help you make an informed choice:
E-pharmacy | Refund Policy | Payment Options | Shipping | Shopper Service | Free Samples for New Customers | Genuine refund policy | Privacy & Security | Shipping Options | Return Policy | Customer Reviews & Ratings | Website User Experience |
ModafinilXL.com | ✔️ | PayPal, e-Check, Visa, MasterCard, AmEx, Bitcoin, and others | Ultra-fast | ✔️✔️✔️ | ✔️ | ✔️ | Good | Various options available | Flexible | ✔️✔️✔️ | Excellent |
BuyModafinilOnline.com | ✔️ | MasterCard, Bitcoin, PayPal, AmEx, e-Check, Zelle, ETH, and others | Ultra-fast | ✔️✔️✔️ | ✔️ | ✔️ | Good | Various options available | Flexible | ✔️✔️✔️ | Exceptional |
BuyModa.org | ✔️️ | AmEx, Zelle, MasterCard, SWIFT wire transfers, PP, and others | Fast | ✔️✔️️ | ❌ | ✔️ | Good | Various options available | Flexible | ✔️✔️ | Good |
Afinil.com | ✔️ | MasterCard, Visa, AmEx, e-Check, PayPal, Zelle, Bitcoin, ETH, and others | Ultra-fast | ✔️✔️✔️ | ✔️ | ✔️ | Good | Various options available | Flexible | ✔️✔️✔️ | Good |
HighStreetPharma.com | ✔️️ | e-Check, credit/debit cards, PayPal, crypto, & gift cards | Fast | ✔️✔️️ | ❌ | ✔️ | Good | Various options available | Flexible | ✔️✔️ | Good |
FreeModafinil.org | ✔️️ | AmEx, PayPal, MasterCard, Zelle, e-Check, ETH, Bitcoin, and other cryptocurrencies | Ultra-fast | ✔️✔️✔️ | ✔️ | ✔️ | Excellent | Various options available | Flexible | ✔️✔️✔️ | Exceptional |
BuyArmodafinil.com | ✔️️ | MasterCard, AmEx, Zelle, e-Check, PayPal, Bitcoin, ETH, and other cryptocurrencies | Ultra-fast | ✔️✔️✔️ | ✔️ | ✔️ | Excellent | Various options available | Flexible | ✔️✔️✔️ | Good |
These pharmacies vary in their pricing & also shipping methods used. Vendors like ModafinilXL, BuyModafinilOnline.com, Adinil.com, & FreeModafinil.org also offer domestic US & domestic UK parcel shipping. It would be advantageous for you to compare prices & coupons offered to identify the vendor that offers the most value for your money.
Safe Inexpensive Modafinil
When it comes to finding an affordable and reliable modafinil-based drug, Modvigil stands out as a top choice. It is known for being safe, well-tolerated, and effective, making it a popular option among users. While it may not be as potent as ModaXL and has a slower onset of action, many people have found it to be highly effective. However, it is important to prioritize your health and safety, so it is recommended to consult your doctor before starting treatment with Modvigil or any other medication.
Here is a table comparing the prices of Modvigil 200 mg 100 pills from different vendors:
Vendor | Price for Modvigil (per pill) |
ModafinilXL | $1.09 |
BuyModafinilOnline | $1.29 |
BuyModa | $1.09 |
Afinil | $1.09 |
HighStreetPharma | $1.05 |
FreeModafinil | $1.09 |
BuyArmodafinil | $1.29 |
Please note that prices may vary, and it’s always a good idea to visit the respective websites for the most up-to-date pricing information.
Best Generic Modafinil for Beginners
If you’re new to the realm of nootropics and finding it difficult to choose the right product to begin with, you have the option of selecting either ModaXL or Modvigil. While ModaXL offers a slightly stronger effect, it is specifically formulated to minimize the risk of negative effects, making it a suitable choice for beginners. Opting for ModaXL as your first preference may be advantageous due to its updated formula and recent development. However, if you’re on a tight budget, Modvigil is a more cost-effective alternative.
Best Generic Modafinil for Power Users
If your profession demands both mental and physical exertion and necessitates prolonged periods of wakefulness, alertness, focus, and physical activity, ModaXL is the ideal choice for you. It surpasses other generic modafinil brands, such as Modvigil and Modalert, in terms of its peak effect, offering up to a 30% greater impact. This particular brand is popular among professionals like truck drivers, shift workers, forklift operators, security operatives, students, executives, and computer programmers, as it provides significant assistance in meeting their job requirements. However, it is crucial to consult your doctor before initiating treatment with ModaXL to ensure its suitability for your specific circumstances.
So, Which Nootropic Is Better?
ModaXL, Modvigil, ArmodaXL, and Artvigil are all reputable medications produced by trustworthy pharmaceutical companies. Whether your goal is to address sleep disorder symptoms or enhance cognitive function for a competitive advantage, any of these options are likely to be effective. However, your budget and the nature of your work will play a role in determining the best choice for you. If you have budget constraints, Modvigil or Artvigil may be more suitable, while the newer versions, ModaXL or ArmodaXL, could be preferred if cost is not a major concern.
It’s important to note that the dissolution rate of ModaXL 200mg is better compared to Modalert and Modvigil 200mg, which is a significant advantage for ModaXL. However, it’s worth remembering that individuals respond to medications differently, and what works best for one person may not be the same for another. The most effective way to determine the ideal medication for you is to try them all. While this could be costly, online pharmacies like ModafinilXL.com often offer combo deals or free trial samples, which can help reduce expenses.
References
- Provigil (modafinil) dosing, indications, interactions, adverse effects, and more. Retrieved: June 26, 2023. Reference.medscape.com.
- Narcolepsy medication modafinil is the world’s first safe ‘smart drug.’ Helen Thomson. Retrieved: June 26, 2023. Theguardian.com.
- Nuvigil (armodafinil) dosing, indications, interactions, adverse effects, and more. Retrieved: June 26, 2023. Reference.medscape.com.
- Armodafinil versus Modafinil in Patients of Excessive Sleepiness Associated with Shift Work Sleep Disorder: A Randomized Double-Blind Multicentric Clinical Trial. By D. V. Tembe, A. Dhavale, et al. Retrieved: October 28, 2022. Ncbi.nlm.nih.gov.
- Modafinil. Retrieved: June 26, 2023. Wikipedia.org.
- Complaint for Injunctive Relief. Retrieved: June 26, 2023. Ftc.gov.
- Nuvigil (armodafinil). By Helen Marshall, BPharm, MRPharmS. Published: December 13, 2022. Medically reviewed by Victor Nguyen, PharmD, MBA. Medicalnewstoday.com.
- Nuvigil Interactions Checker. Retrieved: June 26, 2023. Drugs.com.